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| http://dx.doi.org/10.1016/j.abd.2021.01.011 | DOI Listing |
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Lichen nitidus.
Clin Exp Dermatol
January 2025
Department of Dermatology, Venereology and Leprosy, Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, India.
Article Synopsis
- Lichen nitidus (LN) is a rare skin condition that causes small, shiny, flat-topped bumps mainly in children and young adults, with its cause still unclear but likely linked to immune responses.
- The condition is typically asymptomatic and appears on areas like the trunk, upper limbs, and genitals, with diagnosis often based on a specific histological pattern.
- While LN usually resolves on its own, some cases may persist and require topical treatments, and this review provides insights into its clinical features and management strategies for dermatologists.
Ulcerative Lesions in the Intertriginous Areas of an Adolescent Female Patient: A Case of Inverse Erosive Lichen Planus.
Cureus
December 2024
Dermatology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Lichen planus is a common mucocutaneous disorder that can affect various parts of the body, with its erosive variant typically involving the oral mucosa. This variant rarely affects the skin, and even less commonly, the flexural regions. Here, we present a case of a 14-year-old girl who presented with ulcerated, itchy lesions in the intertriginous areas for one year.
View Article and Find Full Text PDFVulvar Carcinoma in Pregnancy: A Case Report on Diagnosis, Management, and Surgical Outcomes.
Cureus
December 2024
Obstetrics and Gynaecology, Fernandez hospital, Hyderabad, IND.
Vulvar cancer is an uncommon malignancy in reproductive-aged women, and its occurrence during pregnancy is rare. This report presents a case of vulvar squamous cell carcinoma (VSCC) diagnosed perioperatively in a 35-year-old pregnant woman. The patient was incidentally found to have lichen sclerosis and a suspicious vulvar lesion during an emergency cesarean section.
View Article and Find Full Text PDFVaccine-Induced Annular Atrophic Lichen Planus.
Mil Med
January 2025
Dermatology Residency Program, Walter Reed National Military Medical Center, Bethesda, MD 20889, USA.
Annular atrophic lichen planus (AALP) is a chronic subtype of lichen planus that classically does not respond to treatment with topical steroids. An inflammatory reaction in the dermal infiltrate may play a role in the development of AALP, but the exact pathogenesis remains unclear. We present the case of a 54-year-old-female with lesions on her trunk and extremities that developed following vaccination.
View Article and Find Full Text PDFLobaric acid suppresses the stemness potential of colorectal cancer cells through mTOR/AKT.
Biofactors
January 2025
College of Pharmacy, Sunchon National University, Sunchon, Republic of Korea.
Stereocaulon alpinum has been found to have potential pharmaceutical properties due to the presence of secondary metabolites such as usnic acid, atranorin, and lobaric acid (LA) which have anticancer activity. On the other hand, the effect of LA on the stemness potential of colorectal cancer (CRC) cells remains unexplored, and has not yet been thoroughly investigated. In this study, we examined the inhibitory activity of LA from Stereocaulon alpinum against the stemness potential of CRC cells and investigated the possible underlying mechanisms.
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