Sclerosing pneumocytoma is an uncommon pulmonary tumor which generally behaves benignly and occurs predominately in women. Rarely, it is associated with neuroendocrine proliferations such as hyperplasia, tumorlets and carcinoid tumors, which may be observed in relation to the tumor or in the distant lung parenchyma; the mechanism underlying this neuroendocrine differentiation is not clear. We present a case of a 33 year-old male with sclerosing pnemocytoma with coexistent neuroendocrine hyperplasia and combined carcinoid tumorlets. Taking into account the pluripotentiality of the round cells present in the sclerosing pneumocytoma, with positive staining for stem cells markers, it is possible that the different components of this neoplasia share a common origin, in accordance with previously reported findings.
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http://dx.doi.org/10.1016/j.patol.2020.02.009 | DOI Listing |
Int Cancer Conf J
January 2025
Department of Allergy and Respiratory Medicine, Okayama University Hospital, Okayama, Japan.
Pulmonary sclerosing pneumocytoma (PSP) is a rare form of lung cancer that occasionally presents with lymph node and extrapulmonary metastases, and multiple lesions. The treatment of metastatic PSP remains undefined. This study reports the case of a 48-year-old female patient diagnosed with PSP following surgical intervention for a solitary nodule in the left lower lobe.
View Article and Find Full Text PDFIndian J Radiol Imaging
January 2025
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Pulmonary sclerosing pneumocytoma is a rare benign neoplasm typically seen in middle-aged women. The exact preoperative diagnosis is quite challenging considering its nonspecific clinical and radiologic features along with complex histology. Moreover, obtaining an exact histopathological diagnosis can be difficult especially with the small biopsy specimens.
View Article and Find Full Text PDFMedicina (B Aires)
December 2024
Servicio Cirugía Torácica, Hospital Británico, Buenos Aires, Buenos Aires, Argentina.
Pulmonary pneumocytoma, formerly known as sclerosing hemangioma, is a rare, benign tumor that frequently affects women in the 4th and 5th decades of life. Here we present the case of a 17-year-old patient with a diagnosis of sclerosing pneumocytoma with infrequent presentation.
View Article and Find Full Text PDFInsights Imaging
November 2024
Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Zhonghua Bing Li Xue Za Zhi
November 2024
Department of Pathology, Lishui Central Hospital, Zhejiang Province, Lishui 323000, China.
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