New data analysis for BioSAXS at the ESRF.

J Synchrotron Radiat

ESRF - The European Synchrotron, 71 Avenue des Martyrs, 38000 Grenoble, France.

Published: September 2022

The second phase of the ESRF upgrade program did not only provide a new storage ring (Extremely Brilliant Source, EBS) but also allowed several beamlines to be refurbished. The BioSAXS beamline (located on port BM29) was upgraded with a new wiggler source and a larger detector. All analysis software has been rewritten to cope with the increased data flux and continues to provide beamline users with reduced and pre-processed data in real time. This article describes FreeSAS, an open-source collection of various small-angle scattering analysis algorithms needed to reduce and analyze BioSAXS data, and Dahu, the tool used to interface data analysis with beamline control. It further presents the data-processing pipelines for the different data acquisitions modes of the beamline, using either a sample changer for individual homogeneous samples or an inline size-exclusion chromatography setup.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455220PMC
http://dx.doi.org/10.1107/S1600577522007238DOI Listing

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