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Echocardiography interpretation training and internal medicine milestones: A pilot study.
J Formos Med Assoc
January 2025
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Telehealth Center, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:
Background/purpose: The competency-based Internal Medicine Milestones (IMM) assesses physician training outcomes through six key competencies. This pilot study introduced IMM concepts through an echocardiography report interpretation course for postgraduate students (PGYs) and residents (Rs). We aimed to help young physicians understand and track competency development as they receive cardiovascular training, with a view to expanding IMM usage for all junior physicians.
View Article and Find Full Text PDFNonpharmacological Management of Cancer-Related Cachexia: A Systematic Review.
Semin Oncol Nurs
January 2025
Nursing Department, Cyprus University of Technology, Limassol, Cyprus.
Objectives: Cancer-related cachexia affects approximately 50% to 80% of cancer patients and contributes significantly to cancer-related mortality, accounting for 20% of deaths. This multifactorial syndrome is characterized by systemic inflammation, anorexia, and elevated energy expenditure, leading to severe weight loss and muscle wasting. Understanding the underlying mechanisms is critical for developing effective interventions.
View Article and Find Full Text PDFSocial-economic inequalities and early-life exposure to famine contribute to low grip strength: The China National Health Survey.
Nutr Metab Cardiovasc Dis
December 2024
Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing, China; State Key Laboratory of Common Mechanism Research for Major Diseases, Beijing, China. Electronic address:
Background And Aim: The relationship between socio-economic inequalities (SEIs) and early life malnutrition with muscle health remains unclear. This study aims to examine the effects of SEIs and early life exposure to famine on relative hand grip strength (rHGS).
Methods And Results: We analyzed data of 37,008 individuals from the China National Health Survey.
Intravenous injection of PCSK9 gain-of-function mutation in C57BL/6J background mice on Angiotensin II-induced AAA.
Biochim Biophys Acta Mol Basis Dis
January 2025
State Key Laboratory for Innovation and Transformation of Luobing Theory, Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China. Electronic address:
Objective: This study was performed to compare the incidence of Angiotensin II (Ang II)-induced abdominal aortic aneurysms (AAA) between intravenous and intraperitoneal injection of AAV8.mPCSK9 in wild-type (WT) mice with C57BL/6J background and the pathological differences of above model in WT and ApoE mice.
Design: Male WT mice were injected intraperitoneally or intravenously with either a AAV8.
Prospects of bovine milk small extracellular vesicles in veterinary medicine.
Res Vet Sci
January 2025
Laboratory of Food and Environmental Hygiene, Joint Department of Veterinary Medicine, Gifu University, Gifu, Japan; Education and Research Center for Food Animal Health, Gifu University (GeFAH), Gifu, Japan; Joint Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan. Electronic address:
Extracellular vesicles (EV), including exosomes or small EV (sEV) derived from biological fluids, such as milk, have garnered increasing interest in veterinary medicine because of their role in the pathophysiology and understanding of the disease status of the host. Bovine milk serves as a rich source of sEV, containing diverse cargoes of nucleic acids, proteins, and lipids, which play a critical role in intercellular communication and regulation of host status. Although it is more difficult to isolate and purify sEV from bovine milk than from human breast milk, challenges persist in enabling the enrichment and analysis of sEV populations, facilitating the elucidation of their functional roles and prognostic potential in cattle diseases.
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