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Causes of Infertility: Diagnosis and Management With Microfluidic Sperm Sorter. | LitMetric

AI Article Synopsis

  • A married couple struggling with infertility for two and a half years began IVF/ART treatments in December 2021 after previous unsuccessful IUI attempts in 2019.
  • They were advised to use ICSI, which involved sorting male sperm samples with a microfluidic sperm sorter to improve fertilization chances.
  • The male partner had a condition called oligoasthenozoospermia, for which he was given multivitamins and medications, leading to successful blastocyst formation after the ICSI procedure.

Article Abstract

This case study refers to a three-and-a-half-year married couple who visited an infertility clinic and are facing infertility for two-and-a-half years. They started in vitro fertilization/assisted reproduction technology (IVF/ART) procedures from December 2021. In 2019, the couple underwent infertility therapy in Wardha, India, including three intra-uterine insemination (IUI) treatments which failed. The couple was then recommended the intracytoplasmic sperm injection (ICSI) procedure in which the semen sample was separated using a microfluidic sperm sorter for separating good quality sperms. There was no past medical history of both of the partners. Since she was infertile, the desire to have a child was extremely strong. Sadness, helplessness, bewilderment, and frustration are all common feelings associated with infertility. The left fallopian tube delays spillage in females and oligoasthenozoospermia in males; women were detected with secondary infertility and male sperm samples were sorted using a microfluidic sperm sorter and fertilized frozen oocytes for ICSI. As the male partner, in this case, had oligoasthenozoospermia, he was prescribed multivitamins and other medications. After ICSI, the blastocyst formation was good with the use of a microfluidic sperm sorter.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440623PMC
http://dx.doi.org/10.7759/cureus.27674DOI Listing

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