Words that can be easily placed in contexts are more easily processed, yet norms for context availability are limited. Here, participants rated 3,000 words for context availability and sentence availability, a new metric predicted to capture information relating to textual variation. Both variables were investigated alongside other word-level characteristics to explore lexical-semantic space. Analyses demonstrated that context availability and sentence availability are distinct. Context availability covaries with concreteness and imageability, while sentence availability captures information relating to contextual variation, frequency and ambiguity. Analyses of megastudy data showed that both context availability and sentence availability uniquely facilitated lexical decision performance.
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http://dx.doi.org/10.5334/joc.211 | DOI Listing |
Aging Ment Health
January 2025
Department of Psychology, University of Edinburgh, Edinburgh, UK.
Objectives: Ageism occurs across the world, with negative consequences for individuals and societies. In 2016, WHO received a mandate from its Member States to lead the global campaign to combat ageism. To monitor, evaluate, and build evidence for reducing ageism, the availability of a brief, reliable and valid set of indicators of ageism experiences that can be used globally is essential.
View Article and Find Full Text PDFJ Clin Med
December 2024
Division of Ophthalmology, Department of Surgery, UMass Chan-Lahey School of Medicine, Burlington, MA 01805, USA.
Personalizing the management of neovascular age-related macular degeneration (nAMD) poses significant challenges for practicing retina specialists and their patients. This commentary addresses some of these complexities, particularly those that arise in the context of an expanding array of intravitreal agents targeting vascular endothelial growth factor (VEGF) and related retinal disease targets. Many of these newer agents approved by the Food and Drug Administration (FDA) for the treatment of nAMD have labeling that indicates that they can provide non-inferior visual outcomes when compared head-to-head with previously available treatments and can be used at significantly extended dosing intervals in some patients.
View Article and Find Full Text PDFSensors (Basel)
December 2024
School of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Due to its non-contact characteristics, remote photoplethysmography (rPPG) has attracted widespread attention in recent years, and has been widely applied for remote physiological measurements. However, most of the existing rPPG models are unable to estimate multiple physiological signals simultaneously, and the performance of the limited available multi-task models is also restricted due to their single-model architectures. To address the above problems, this study proposes MultiPhys, adopting a heterogeneous network fusion approach for its development.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Science of Functional Recovery and Reconstruction, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
: Developing high-performance artificial intelligence (AI) models for rare diseases is challenging owing to limited data availability. This study aimed to evaluate whether a novel three-class annotation method for preparing training data could enhance AI model performance in detecting osteosarcoma on plain radiographs compared to conventional single-class annotation. : We developed two annotation methods for the same dataset of 468 osteosarcoma X-rays and 378 normal radiographs: a conventional single-class annotation (1C model) and a novel three-class annotation method (3C model) that separately labeled intramedullary, cortical, and extramedullary tumor components.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Programa de Comunicación Celular en Cáncer, Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, Santiago 7550000, Chile.
DUX4 is typically a repressed transcription factor, but its aberrant activation in Facioscapulohumeral Muscular Dystrophy (FSHD) leads to cell death by disrupting muscle homeostasis. This disruption affects crucial processes such as myogenesis, sarcolemma integrity, gene regulation, oxidative stress, immune response, and many other biological pathways. Notably, these disrupted processes have been associated, in other pathological contexts, with the presence of connexin (Cx) hemichannels-transmembrane structures that mediate communication between the intracellular and extracellular environments.
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