Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629310PMC
http://dx.doi.org/10.1007/s11274-022-03397-zDOI Listing

Publication Analysis

Top Keywords

correction mitigating
4
mitigating toxicity
4
toxicity palmitoylated
4
palmitoylated analogue
4
analogue α-melanocyte
4
α-melanocyte stimulating
4
stimulating hormone11-13
4
hormone11-13 conjugation
4
conjugation gold
4
gold nanoparticle
4

Similar Publications

Efficacy and durability of cobalt sulfide nanoparticles and axial sulfur-coordinated cobalt single-atom composite sites in hydrogenative nitroaromatics decontamination.

J Colloid Interface Sci

January 2025

Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Ministry of Education, School of Environmental Science and Engineering, Guangzhou University, Guangzhou 510006, China. Electronic address:

Emerging single-atom materials and metal sulfides hold significant promise as alternatives to precious metal catalysts for nitroaromatics conversion; however, their intrinsic activity and durability remain insufficiently understood. Herein, sulfur and nitrogen co-doped carbon matrices incorporating CoS nanoparticles and single-atom Co with Co-N-S coordination were constructed through a facile pyrolysis approach. Advanced characterization techniques, such as X-ray absorption fine structure (XAFS) and aberration-corrected electron microscopy, unveiled unique structural features underpinning exceptional catalytic efficiency and recyclability.

View Article and Find Full Text PDF

Epidemiological methods in transition: Minimizing biases in classical and digital approaches.

PLOS Digit Health

January 2025

Social Physics and Complexity (SPAC) Lab, LIP-Laboratory for Instrumentation and Experimental Particle Physics, Lisboa, Portugal.

Epidemiology and Public Health have increasingly relied on structured and unstructured data, collected inside and outside of typical health systems, to study, identify, and mitigate diseases at the population level. Focusing on infectious diseases, we review the state of Digital Epidemiology at the beginning of 2020 and how it changed after the COVID-19 pandemic, in both nature and breadth. We argue that Epidemiology's progressive use of data generated outside of clinical and public health systems creates several technical challenges, particularly in carrying specific biases that are almost impossible to correct for a priori.

View Article and Find Full Text PDF

Highly effective batch effect correction method for RNA-seq count data.

Comput Struct Biotechnol J

December 2024

Department of Computer Science and Information Science, California State University San Marcos, 333 S. Twin Oaks Valley Rd, San Marcos, CA 92096, USA.

RNA sequencing (RNA-seq) has become a cornerstone of transcriptomics, providing detailed insights into gene expression across diverse biological conditions and sample types. However, RNA-seq data are often confounded by batch effects, systematic non-biological variations that compromise data reliability and obscure true biological differences. To address these challenges, we introduce ComBat-ref, a refined batch effect correction method designed to enhance the statistical power and reliability of differential expression analysis in RNA-seq data.

View Article and Find Full Text PDF

Pym-18a, a novel pyrimidine derivative ameliorates glucocorticoid induced osteoblast apoptosis and promotes osteogenesis via autophagy and PINK 1/Parkin mediated mitophagy induction.

Biochem Pharmacol

January 2025

Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201002, India. Electronic address:

Glucocorticoid-induced osteoporosis (GIOP) is the most common type of secondary osteoporosis, marked by reduced bone density and impaired osteoblast function. Current treatments have serious side effects, highlighting the need for new drug candidates. Pyrimidine derivatives have been noted for their potential in suppressing osteoclastogenesis, but their effects on osteogenesis and GIOP remain underexplored.

View Article and Find Full Text PDF

High cadmium (Cd) concentrations pose a threat to aquatic life globally. This study examined the efficiency of adding purslane (Portulaca oleracea L.) leaf powder (PLP) to Oreochromis niloticus diets on Cd's negative effects.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!