AI Article Synopsis
- The medial pulvinar, a part of the pulvinar thalamic nucleus, is connected to various cortical areas responsible for sensory processing, but its role in non-visual modalities is not well understood.
- Research involving macaque monkeys showed that the medial pulvinar contains neurons responsive to visual, auditory, and audiovisual stimuli, indicating its capacity for multisensory integration.
- The study found that the medial pulvinar often exhibits suppressive and subadditive responses during multisensory input, suggesting its involvement in how different sensory modalities interact.
Article Abstract
The pulvinar is a heterogeneous thalamic nucleus, which is well developed in primates. One of its subdivisions, the medial pulvinar, is connected to many cortical areas, including the visual, auditory, and somatosensory cortices, as well as with multisensory areas and premotor areas. However, except for the visual modality, little is known about its sensory functions. A hypothesis is that, as a region of convergence of information from different sensory modalities, the medial pulvinar plays a role in multisensory integration. To test this hypothesis, 2 macaque monkeys were trained to a fixation task and the responses of single-units to visual, auditory, and auditory-visual stimuli were examined. Analysis revealed auditory, visual, and multisensory neurons in the medial pulvinar. It also revealed multisensory integration in this structure, mainly suppressive (the audiovisual response is less than the strongest unisensory response) and subadditive (the audiovisual response is less than the sum of the auditory and the visual responses). These findings suggest that the medial pulvinar is involved in multisensory integration.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10110443 | PMC |
| http://dx.doi.org/10.1093/cercor/bhac337 | DOI Listing |
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