The article presents the results of using plasmapheresis in 8 patients with high arterial hypertension refractory to drug therapy. After 2 plasmapheresis procedures a stable BP decrease was observed in all patients allowing a further decrease of hypotensive drug administration. The hypotensive effect of plasmapheresis was accompanied by an improvement of the eye fundus and of renal function, decreased proteinuria and increased sensitivity to hypotensive therapy. Possible mechanisms of post-plasmapheresis BP lowering are discussed.
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