A site-specific method for the preparation of N-glycosylated peptides is described. Incorporation of a peptide backbone thioamide linkage adjacent to an Asp residue facilitates a Ag -promoted, site-specific conversion to N-glycosylated Asn residues in peptides.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826000 | PMC |
http://dx.doi.org/10.1002/anie.202210367 | DOI Listing |
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