RNA editing in Mycobacterium tuberculosis.

Microbiol Res

Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Vanderbilt Tuberculosis Center, Vanderbilt University School of Medicine, Nashville, TN, USA. Electronic address:

Published: November 2022

RNA editing, while studied thoroughly in humans, has been sporadically described in bacteria, and to our knowledge, has not been reported in Mycobacterium tuberculosis (Mtb). After thorough quality control and validation by repeated sequencing, by comparing sequences from RNA and DNA from high-throughput sequencing data, we report the first finding of three RNA editing events in two Mtb isolates.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332325PMC
http://dx.doi.org/10.1016/j.micres.2022.127174DOI Listing

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