AI Article Synopsis
- FDG PET/CT is a valuable imaging technique for assessing inflammation and synovial metabolic activity in rheumatoid arthritis (RA), using standard uptake values for evaluation.
- NaF PET/CT helps in determining osteoblastic activity in the joints and can also evaluate conditions like vasculitis and aortic calcification associated with RA.
- Emerging studies on novel tracers may enhance RA diagnosis and treatment, potentially leading to theranostic applications in the future.
Article Abstract
[F]fluorodeoxyglucose (FDG) PET/CT can be used to image the inflammation in rheumatoid arthritis. Specifically, the synovial metabolic activity can be evaluated visually and measured using standard uptake values. Fluorine-18-labeled Sodium fluoride (NaF) PET/CT can be used to determine synovial osteoblastic activity. Response assessment using FDG PET/CT is routine in many cancers and this is now an emerging technique for rheumatoid arthritis. Vasculitis in rheumatoid arthritis (RA) can be also studied with FDG PET/CT and aortic calcification with NaF PET/CT. These techniques could be useful in determining RA disease severity. FDG PET/CT is a useful technique to exclude underlying malignancy when RA does not follow the expected course. A number of novel tracers are being studied with regard to their applicability in rheumatoid arthritis and some of these could even be used in a theranostic manner in the future.
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| http://dx.doi.org/10.23736/S1824-4785.22.03461-6 | DOI Listing |
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