AI Article Synopsis

  • Myocardial strain imaging is becoming crucial in cardiac MRI for detecting early left ventricular dysfunction, with techniques like fast strain encoded imaging (fSENC) and feature tracking (FT) showing promise alongside left-ventricular long axis strain (LVLAS).* -
  • In a study involving 40 patients with chest pain, LVLAS was found to be effective in identifying myocardial dysfunction compared to fSENC, while FT struggled to differentiate between different types of cardiac issues.* -
  • Both fSENC and LVLAS demonstrated good reproducibility in measuring myocardial strain, suggesting they are reliable methods for assessing cardiac health prior to traditional measures like left-ventricular ejection fraction (LVEF).*

Article Abstract

Background: Myocardial strain imaging has gained importance in cardiac magnetic resonance (CMR) imaging in recent years as an even more sensitive marker of early left ventricular dysfunction than left-ventricular ejection fraction (LVEF). fSENC (fast strain encoded imaging) and FT (feature tracking) both allow for reproducible assessment of myocardial strain. However, left-ventricular long axis strain (LVLAS) might enable an equally sensitive measurement of myocardial deformation as global longitudinal or circumferential strain in a more rapid and simple fashion.

Methods: In this study we compared the diagnostic performance of fSENC, FT and LVLAS for identification of cardiac pathology (ACS, cardiac-non-ACS) in patients presenting with chest pain (initial hscTnT 5-52 ng/l). Patients were prospectively recruited from the chest pain unit in Heidelberg. The CMR scan was performed within 1 h after patient presentation. Analysis of LVLAS was compared to the GLS and GCS as measured by fSENC and FT.

Results: In total 40 patients were recruited (ACS n = 6, cardiac-non-ACS n = 6, non-cardiac n = 28). LVLAS was comparable to fSENC for differentiation between healthy myocardium and myocardial dysfunction (GLS-fSENC AUC: 0.882; GCS-fSENC AUC: 0.899; LVLAS AUC: 0.771; GLS-FT AUC: 0.740; GCS-FT: 0.688), while FT-derived strain did not allow for differentiation between ACS and non-cardiac patients. There was significant variability between the three techniques. Intra- and inter-observer variability (OV) was excellent for fSENC and FT, while for LVLAS the agreement was lower and levels of variability higher (intra-OV: Pearson > 0.7, ICC > 0.8; inter-OV: Pearson > 0.65, ICC > 0.8; CoV > 25%).

Conclusions: While reproducibility was excellent for both FT and fSENC, it was only fSENC and the LVLAS which allowed for significant identification of myocardial dysfunction, even before LVEF, and therefore might be used as rapid supporting parameters for assessment of left-ventricular function.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442977PMC
http://dx.doi.org/10.1186/s12880-022-00886-3DOI Listing

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