The acquisition of bio-signal from the human body requires a strict experimental setup and ethical approvements, which leads to limited data for the training of classifiers in the era of big data. It will change the situation if synthetic data can be generated based on real data. This article proposes such a kind of multiple channel electromyography (EMG) data enhancement method using a deep convolutional generative adversarial network (DCGAN). The generation procedure is as follows: First, the multiple channels of EMG signals within sliding windows are converted to grayscale images through matrix transformation, normalization, and histogram equalization. Second, the grayscale images of each class are used to train DCGAN so that synthetic grayscale images of each class can be generated with the input of random noises. To evaluate whether the synthetic data own the similarity and diversity with the real data, the classification accuracy index is adopted in this article. A public EMG dataset (that is, ISR Myo-I) for hand motion recognition is used to prove the usability of the proposed method. The experimental results show that adding synthetic data to the training data has little effect on the classification performance, indicating the similarity between real data and synthetic data. Moreover, it is also noted that the average accuracy (five classes) is slightly increased by 1%-2% for support vector machine (SVM) and random forest (RF), respectively, with additional synthetic data for training. Although the improvement is not statistically significant, it implies that the generated data by DCGAN own its new characteristics, and it is possible to enrich the diversity of the training dataset. In addition, cross-validation analysis shows that the synthetic samples have large inter-class distance, reflected by higher cross-validation accuracy of pure synthetic sample classification. Furthermore, this article also demonstrates that histogram equalization can significantly improve the performance of EMG-based hand motion recognition.
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http://dx.doi.org/10.3389/fbioe.2022.909653 | DOI Listing |
ACS Synth Biol
January 2025
Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94702, United States.
Naturally evolved and synthetically designed forms of compartmentalization benefit encapsulated function by increasing local concentrations of substrates and protecting cargo from destabilizing environments and inhibitors. Crucial to understanding the fundamental principles of compartmentalization are experimental systems enabling the measurement of the permeability rates of small molecules. Here, we report the experimental measurement of the small-molecule permeability of a 40 nm icosahedral bacterial microcompartment shell.
View Article and Find Full Text PDFPLoS One
January 2025
Violence and Society Centre, City St George's, University of London, London, United Kingdom.
Violence has been analysed in silo due to difficulties in accessing data and concerns for the safety of those exposed. While there is some literature on violence and its associations using individual datasets, analyses using combined sources of data are very limited. Ideally data from the same individuals would enable linkage and a longitudinal understanding of experiences of violence and their (health) impacts and consequences.
View Article and Find Full Text PDFCurr Opin Crit Care
January 2025
Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Purpose Of Review: This review aims to examine recent advances in the understanding of injury-induced endotheliopathy and therapeutics to mitigate its development in critically injured patients.
Recent Findings: Clinical studies have clearly demonstrated that syndecan-1 ectodomains can be found in circulation after various types of trauma and injury and correlates with worse outcomes. As the mechanisms of endotheliopathy are better understood, pathologic hyperadhesive forms of von Willebrand factor, along with a relative deficiency of its cleaving enzyme, a disintegrin and metalloprotease with thrombospondin type I motifs, member 13 (ADAMTS13), have emerged as additional biomarkers.
JAMA Netw Open
January 2025
Division of Intramural Research, National Institute on Minority Health and Health Disparities, Bethesda, Maryland.
Importance: Cigarette companies have been introducing synthetic cooling agent menthol-mimicking cigarettes into the US marketplace as menthol cigarette bans are implemented. These cigarettes may reduce the public health benefits of menthol cigarette bans.
Objective: To examine the epidemiology of the use of synthetic cooling agent menthol-mimicking cigarettes among adults in the US.
ACS Infect Dis
January 2025
Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais 36036-900, Brazil.
Schistosomiasis is the infection caused by and constitutes a worldwide public health problem. The parasitological recommended method and serological methods can be used for the detection of eggs and antibodies, respectively. However, both have limitations, especially in low endemicity areas.
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