Phyllodes tumors, previously known as cystosarcoma phyllodes, are fibroepithelial tumors that consist of epithelial and cellular stromal components. These tumors have a predilection to recur after wide local excision and to attain massive sizes. They account for less than 0.5% of cases of all breast neoplasms and are primarily found in the third to fourth decade of life, and rarely in adolescence. However, less than 25 cases are reported to date wherein this tumor is found in adolescent females, with this case being one of those. This is a report of a rare case of a 12-year-old premenarchal female with bilateral phyllodes tumor, highlighting its peculiarities, diagnostic features, and surgical management in view of the patient's age and quality of life.
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Malignant phyllodes tumor of the breast with bilateral ductal carcinoma in situ and postoperative distant metastasis: a case report.
Transl Cancer Res
November 2024
Department of Nuclear Medicine, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China.
Background: Phyllodes tumors (PTs) are breast neoplasms with varying degrees of malignancy, posing challenges in diagnosis and management. This case report focuses on a rare case of malignant phyllodes tumor of the breast (MPTB) in a 35-year-old woman.
Case Description: This case report presents a complex scenario of a patient with extensive breast abnormalities, including a malignant PT in the left breast, ductal carcinoma in both breasts, with axillary lymph node involvement.
Malignant Phyllodes Tumor of the Breast With Multiple Cutaneous Metastasis Resembling Pleomorphic Rhabdomyosarcoma.
Am J Dermatopathol
December 2024
Department of Pathology, Rutgers University New Jersey Medical School, Newark, NJ; and.
Malignant phyllodes tumor (PT) of the breast is a rare fibroepithelial neoplasm that shows variegated histomorphology and an aggressive clinical course. Cutaneous metastases are rare. A 68 year old woman presented with a palpable left breast mass identified on a routine breast exam.
View Article and Find Full Text PDFUnexpected Clinical Status of Phyllodes Tumor of the Breast: Massive Bleeding.
Cureus
August 2024
Surgery, University of Health Sciences, Haseki Training and Research Hospital, Istanbul, TUR.
Regardless of whether they are benign or malignant, phyllodes tumors can behave unpredictably and aggressively. Sometimes they grow so quickly and can cause clinically different, rare, and difficult situations to manage. Because of these characteristics, they can be fatal, even if they are benign.
View Article and Find Full Text PDFCase report: Possible role of low-dose PEM for avoiding unneeded procedures associated with false-positive or equivocal breast MRI results.
Front Oncol
July 2024
Department of Physics, Lakehead University, Thunder Bay, ON, Canada.
Article Synopsis
- - Contrast-enhanced breast MRI is recommended for high-risk women but has limitations, such as false positives and increased patient anxiety due to hormonal sensitivity and the potential for overdiagnosis.
- - Breast-targeted PET imaging offers higher specificity and can detect cancers regardless of breast density or hormonal fluctuations, although traditional PET involves high radiation levels, limiting its use in some cases.
- - A case study using the low-dose Radialis PET imager for a 33-year-old patient highlighted its ability to detect lesions with low metabolic activity; however, it did not reveal any malignant areas in this instance, resulting in surgical interventions for tumor removal.
Pneumothorax as a rare presentation in a case of phyllodes tumor of breast with cavitating lung metastasis.
J Cancer Res Ther
April 2024
Department of Medical Oncology, IRCH, All India Institute of Medical Sciences, New Delhi, India.
The lung is the most common site of metastases in the case of phyllodes tumor of the breast followed by bone. However, pneumothorax as a presenting complaint in a patient of bilateral cavitating lung metastases from malignant phyllodes tumor of the breast has never been reported to our knowledge. We herein report a case of a 34-year-old female presenting with sudden onset of chest pain in already existing lung metastases who on imaging showed the development of bilateral pneumothorax.
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