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http://dx.doi.org/10.1017/cjn.2022.293 | DOI Listing |
Can J Neurol Sci
September 2023
Department of Neurology, Teikyo University School of Medicine, Tokyo, Japan.
BMJ Case Rep
May 2021
Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan, USA.
Stiff-person syndrome (SPS) is a rare progressive neurological disorder characterised by painful muscle spasms and progressive muscle rigidity, leading in some cases to impaired ambulation. Anti-amphiphysin positive SPS is a paraneoplastic variant, frequently associated with breast carcinomas and small cell lung cancers. We report the case of a 53-year-old patient who developed symptoms of anti-amphiphysin positive SPS 3 years before being diagnosed with invasive ductal carcinoma.
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