First cases of oligodontia as a manifestation of the Zika virus congenital syndrome.

Objective: The aim of this study was to characterize the oral alterations in patients with the congenital syndrome caused by Zika virus infection (CZS).

Study Design: Ten children with CZS from the Association of Mothers of Microcephaly, Montes Claros, Minas Gerais State, Brazil were included. Data collection consisted of an interview with the parents, intraoral examination, and panoramic radiography.

Results: Oligodontia was found in 2 children. The first child, a 3-year-old boy, had 12 dental absences (2 primary maxillary lateral incisors, 2 primary mandibular lateral incisors, 2 primary maxillary canines, 1 primary mandibular canine, 1 primary maxillary first molar, 2 primary mandibular second molars, and 2 primary maxillary second molars), and the second child, a 5-year-old boy, showed 15 missing teeth (4 primary central incisors, 1 primary maxillary lateral incisor right, 2 primary mandibular lateral incisors, 2 primary maxillary canines, 1 primary mandibular canine, 1 primary mandibular first molar, and 4 primary second molars).

Conclusions: This study is the first report of oligodontia in Brazilian patients with CZS. Further studies with CZS patients are needed to better understand the occurrence and the association between Zika virus and oligodontia.