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- The study aimed to investigate how different patterns of blood flow in the kidneys, assessed through Doppler ultrasound, can indicate the severity of venous congestion and predict kidney function impairment in patients suffering from acute decompensated chronic heart failure (ADCHF).
- Conducted on 75 ICU patients, the study analyzed the blood flow patterns (normal, biphasic, monophasic) and measured sodium concentration in urine after diuretic treatment to monitor kidney injury and other complications.
- Results revealed that patients with a monophasic blood flow pattern had a significantly higher incidence of acute kidney injury (100%) and were more likely to experience in-hospital death and diuretic resistance compared to those with normal or biphasic patterns
Effects of Triamterene in Hospitalized Patients with Heart Failure and Diuretic Resistance: A Randomized Clinical Trial.
J Clin Pharmacol
December 2023
Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Due to the potential benefits of triamterene in diuretic resistance, this study was performed to assess whether triamterene add-on to the standard treatment of heart failure (HF)-related diuretic resistance improves outcomes. A randomized clinical trial was performed on 45 hospitalized patients with HF with reduced ejection fraction who had diuretic resistance. Patients were randomized to receive either triamterene 50 mg plus hydrochlorothiazide 25 mg (n = 23) or hydrochlorothiazide 50 mg alone (n = 22) until hospital discharge.
View Article and Find Full Text PDFDiuretic Resistance-A Key to Identifying Clinically Significant Worsening Renal Function in Heart Failure?
Mayo Clin Proc
September 2022
School of Medicine, University College Dublin, Dublin, Ireland. Electronic address:
[Idiopathic intracranial hypertension and factor V Leiden mutation].
J Mal Vasc
July 2014
Service d'imagerie médicale, hôpital universitaire Taher Sfar Mahdia, Hiboun 5111, Tunisie.
Activated proteinC resistance is a frequent prothrombotic abnormality. In most cases it is due to factorV Leiden mutation by nucleotide G1691A substitution. This recently described thrombophilic defect of activated proteinC resistance has been postulated to be implicated in the pathogenesis of idiopathic intracranial hypertension (IIH).
View Article and Find Full Text PDFRenal dysfunction in acute congestive heart failure: a common problem for cardiologists and nephrologists.
Heart Fail Rev
November 2014
Nephrology and Dialysis Unit, Humanitas Clinical and Research Center, Via Manzoni 56, 20089, Rozzano, Milan, Italy,
The term acute heart failure (AHF) refers to a clinical syndrome with typical symptoms and signs, in which a structural or functional heart abnormality leads to defective oxygen delivery. The term cardiorenal syndrome has been proposed to outline the strict interplay between cardiac and renal function. In the setting of acute cardiac decompensation, acute kidney injury (AKI) is generally referred to as cardiorenal syndrome type 1.
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