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Macromolecular interactions and geometrical confinement determine the 3D diffusion of ribosome-sized particles in live cells.
Proc Natl Acad Sci U S A
January 2025
Department of Chemical Engineering, Stanford University, Stanford, CA 94305.
The crowded bacterial cytoplasm is composed of biomolecules that span several orders of magnitude in size and electrical charge. This complexity has been proposed as the source of the rich spatial organization and apparent anomalous diffusion of intracellular components, although this has not been tested directly. Here, we use biplane microscopy to track the 3D motion of self-assembled bacterial genetically encoded multimeric nanoparticles (bGEMs) with tunable size (20 to 50 nm) and charge (-3,240 to +2,700 e) in live cells.
View Article and Find Full Text PDFOptimizing Post-activation Performance Enhancement in Athletic Tasks: A Systematic Review with Meta-analysis for Prescription Variables and Research Methods.
Sports Med
January 2025
School of Athletic Performance, Shanghai University of Sport, No. 200, Henren Road, Shanghai, 200438, China.
Background: Post-activation performance enhancement (PAPE) has demonstrated efficacy in acutely improving athletic performance. However, its distinction from general warm-up (GW) effects remains ambiguous, and experimental designs adopted in most PAPE studies exhibit important limitations.
Objectives: The aims of this work are to (i) examine the effects of research methodology on PAPE outcomes, (ii) explore PAPE outcomes in relation to comparison methods, performance measures, GW comprehensiveness, recovery duration, participants' characteristics, conditioning activity (CA) parameters, and (iii) make recommendations for future PAPE experimental designs on the basis of the results of the meta-analysis.
Muscular Performance and Blood Pressure After Different Pre-Strength Training Strategies in Recreationally Strength-Trained Women: Cross-Over Trial.
J Cardiovasc Dev Dis
December 2024
Postgraduate Program in Physical Education, Universidade Federal do Rio de Janeiro (EEFD/UFRJ), Rio de Janeiro 21941-599, Brazil.
Background: This study aimed to investigate the acute effects of different pre-ST strategies on muscular performance and blood pressure (BP) responses in recreationally strength-trained women.
Methods: Twelve overweight women with normal BP were recruited and performed six experimental protocols in a randomized order: (1) control protocol (CC), where BP was assessed without exercises performed; (2) ST; (3) foam rolling warm-up followed by ST (FR + ST); (4) specific warm-up followed by ST (SW + ST); (5) aerobic exercise followed by ST (AE + ST); and (6) stretching exercises followed by ST (SE + ST). ST consisted of three sets at 80% of 10 repetition maximum with a self-suggested rest interval between sets for bench press, back squat, bench press 45°, front squat, lat pull-down, leg press, shoulder press, and leg extension.
Bidimensional Increment Entropy for Texture Analysis: Theoretical Validation and Application to Colon Cancer Images.
Entropy (Basel)
January 2025
LARIS, SFR MATHSTIC, Univ Angers, F-49000 Angers, France.
Entropy algorithms are widely applied in signal analysis to quantify the irregularity of data. In the realm of two-dimensional data, their two-dimensional forms play a crucial role in analyzing images. Previous works have demonstrated the effectiveness of one-dimensional increment entropy in detecting abrupt changes in signals.
View Article and Find Full Text PDFEvent-triggered adaptive compensation control for stochastic nonlinear systems with multiple failures: An improved switching threshold strategy.
ISA Trans
January 2025
School of Mathematics and Physics, Qingdao University of Science and Technology, Qingdao 266061, China; Qingdao Innovation Center of Artificial Intelligence Ocean Technology, Qingdao 266061, China; The Research Institute for Mathematics and Interdisciplinary Sciences, Qingdao University of Science and Technology, Qingdao 266061, China. Electronic address:
This paper considers the event-triggered adaptive fault-tolerant control (FTC) problem for a class of stochastic nonlinear systems suffering from finite number of actuator failures and abrupt system external failure. Unlike existing event-triggered mechanisms (ETMs), this paper proposes an improved switching threshold mechanism (STM) that effectively addresses the potential system security hazards caused by large signal impulses when both the magnitude size of the controller and its rate of change are too large, while also saving energy consumption. Especially, when the occurrence of both actuator failure and system external failure may lead to over-change rate of the controller, by using the multi-dimensional Taylor network (MTN) approximation technique, the adaptive fault-tolerant control scheme designed based on the improved STM not only has lower resource consumption, but also indirectly improves the control performance of the system by ensuring the system security operation.
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