N-Glycans Are Stratum Corneum Biomarkers of Aging Skin.

J Invest Dermatol

L'Oréal Research and Innovation, Aulnay-sous-Bois, France.

Published: March 2023

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Source
http://dx.doi.org/10.1016/j.jid.2022.07.023DOI Listing

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N-Glycan oligosaccharides are thought to play multiple, important roles in a variety of biological events. However, N-glycan profiles in the stratum corneum of human skin have not yet been studied in detail. To clarify the N-glycan profiles in the stratum corneum of normal and ichthyotic epidermis, N-glycan profiles were studied by high-performance liquid chromatography using normal human epidermal samples and scales from hyperkeratotic skin of ichthyosis patients.

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