In this issue of Molecular Cell, Wang et al. investigate the Warburg effect in proliferating cells and demonstrate that lactate fermentation is a secondary mechanism activated after mitochondrial shuttles exceed their capacity to oxidize cytosolic NADH.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888598 | PMC |
http://dx.doi.org/10.1016/j.molcel.2022.08.004 | DOI Listing |
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