Acute compartment syndrome (ACS) is a potential orthopedic emergency that leads, without prompt diagnosis and immediate treatment with surgical fasciotomy, to permanent disability. The role of regional anesthesia (RA) for analgesia in patients at risk for ACS remains unjustifiably controversial. This critical review aims to improve the perception of the published literature to answer the question, whether RA techniques actually delay or may even help to hasten the diagnosis of ACS. According to literature, peripheral RA alone does not delay ACS diagnosis and surgical treatment. Only in 4 clinical cases, epidural analgesia was associated with delayed ACS diagnosis.
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http://dx.doi.org/10.1016/j.anclin.2022.06.001 | DOI Listing |
J Vasc Bras
December 2024
Universidade Positivo - UP, Curitiba, PR, Brasil.
The lower limb is vascularized by the femoral artery, which continues as the popliteal artery. After the distal margin of the popliteus muscle, the popliteal artery divides into the anterior and posterior tibial arteries. Anatomical variations in the bifurcation of the popliteal artery are frequent.
View Article and Find Full Text PDFCompartment syndrome caused by Streptococcus pyogenes (Group A Streptococcus) has rarely been documented. We report the case of a 53-year-old male, hypertensive, who developed compartment syndrome and myositis in the right lower limb. The patient underwent emergency fasciotomies of the anterior, lateral, superficial posterior and deep posterior compartments of the leg and two subsequent surgical debridements, in addition to receiving antibiotic treatment and delayed closure of the fasciotomies with grafts.
View Article and Find Full Text PDFThe aim of this systematic review and meta-analysis was to evaluate and compare the effectiveness of surgical fasciotomy and conservative management for chronic exertional compartment syndrome (CECS) concerning symptom relief, functional recovery, and patient satisfaction. A comprehensive search of PubMed, Scopus, Google Scholar, and Cochrane Library identified studies comparing surgical fasciotomy with conservative management for CECS. Four studies met the inclusion criteria, comprising both retrospective and prospective cohort designs.
View Article and Find Full Text PDFInt J Sports Phys Ther
January 2025
Department of Physiotherapy Centre for Health and Rehabilitation, University College Absalon.
Background: Medial tibial stress syndrome (MTSS) is a common overuse injury characterized by activity-induced pain along the distal medial tibial border. Current best practice includes rest and progressive resistance training. However, some patients with MTSS may be unable to tolerate the loading during exercise.
View Article and Find Full Text PDFJ Biomol Struct Dyn
January 2025
College of Applied Medical Sciences, lmam Abdulrahman Bin Faisal University (lAU), Dammam, Saudi Arabia.
The present study explores the conformational dynamics of the membrane protein of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) within the Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) complex using an all-atomistic molecular dynamics simulation approach. Significant structural changes were observed in the N-terminal, C-terminal, transmembrane, and beta-sheet sandwich domains of the MERS-CoV membrane protein. This study also highlights the structural similarities between the MERS-CoV and the SARS-CoV-2 membrane proteins, particularly in how both exhibit a distinct kink in the transmembrane helix caused by aromatic residue-lipid interactions.
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