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Congenital urethral diverticulum with a large stone in a 16-year-old male: a case report.
BMC Urol
January 2025
Department of Urology, Hama National Hospital, Hama, Syria.
Background: Urethral diverticulum is a sac-like dilation that extends from the urethral lumen and is connected to it. It can either be congenital or acquired, with the latter being more common. The development of calculi is rare in such patients.
View Article and Find Full Text PDFAutologous haematopoietic stem cell transplantation for treatment of multiple sclerosis and neuromyelitis optica spectrum disorder - recommendations from ECTRIMS and the EBMT.
Nat Rev Neurol
January 2025
Department of Neuroscience, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Autologous haematopoietic stem cell transplantation (AHSCT) is a treatment option for relapsing forms of multiple sclerosis (MS) that are refractory to disease-modifying therapy (DMT). AHSCT after failure of high-efficacy DMT in aggressive forms of relapsing-remitting MS is a generally accepted indication, yet the optimal placement of this approach in the treatment sequence is not universally agreed upon. Uncertainties also remain with respect to other indications, such as in rapidly evolving, severe, treatment-naive MS, progressive MS, and neuromyelitis optica spectrum disorder (NMOSD).
View Article and Find Full Text PDFImmunotherapies for sepsis and the impact of study design.
BMJ
January 2025
Critical Care Medicine Branch, National Heart, Lung, and Blood Institute and Critical Care Medicine Department, NIH Clinical Center, Bethesda, MD, USA.
Hospital Health Information Exchange Network Density and Predictors Across U.S. Hospital Referral Regions.
Appl Clin Inform
January 2025
Anesthesiology/Institute for Informatics, Washington University in Saint Louis, Saint Louis, United States.
Objective To develop a measure of Health Information Exchange (HIE) for characterizing the density of inter-hospital HIE connections and identify regional characteristics associated with HIE network density Materials and Methods HIE network density was measured as the proportion of hospital pairs within a region that are connected through HIE. The 2022 American Hospital Association's Information Technology Supplement survey was used to calculate HIE network density for US hospital referral regions (HRRs). Bivariate tests and multivariable regression were used to characterize hospital, electronic health record (EHR) vendor, and resident characteristics associated with HIE network density.
View Article and Find Full Text PDFDosage of botulinum toxin in patients undergoing treatment for hemifacial spasm: is there modification during follow-up?
Arq Neuropsiquiatr
January 2025
Universidade Federal do Rio Grande do Norte, Hospital Universitário Onofre Lopes, Serviço de Neurologia, Natal RN, Brazil.
Background: The movement disorder known as hemifacial spasm is characterized by involuntary contractions of the muscles that are innervated by the facial nerve. The treatment of choice for this condition is botulinum toxin injections.
Objective: To analyze the botulinum toxin dosage in patients undergoing treatment for hemifacial spasm during a 14-year period.
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