Purpose: Various studies have investigated 3-dimensional (3D)-printed implants using Ti-6Al-4V powder; however, multi-root 3D-printed implants have not been fully investigated. The purpose of this study was to explore the stability of multirooted 3D-printed implants with lattice and solid structures. The secondary outcomes were comparisons between the 2 types of 3D-printed implants in micro-computed tomographic and histological analyses.
Methods: Lattice- and solid-type 3D-printed implants for the left and right mandibular third premolars in beagle dogs were fabricated. Four implants in each group were placed immediately following tooth extraction. Implant stability measurement and periapical X-rays were performed every 2 weeks for 12 weeks. Peri-implant bone volume/tissue volume (BV/TV) and bone mineral density (BMD) were measured by micro-computed tomography. Bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO) were measured in histomorphometric analyses.
Results: All 4 lattice-type 3D-printed implants survived. Three solid-type 3D-printed implants were removed before the planned sacrifice date due to implant mobility. A slight, gradual increase in implant stability values from implant surgery to 4 weeks after surgery was observed in the lattice-type 3D-printed implants. The marginal bone change of the surviving solid-type 3D-printed implant was approximately 5 mm, whereas the value was approximately 2 mm in the lattice-type 3D-printed implants. BV/TV and BMD in the lattice type 3D-printed implants were similar to those in the surviving solid-type implant. However, BIC and BAFO were lower in the surviving solid-type 3D-printed implant than in the lattice-type 3D-printed implants.
Conclusions: Within the limits of this preclinical study, 3D-printed implants of double-rooted teeth showed high primary stability. However, 3D-printed implants with interlocking structures such as lattices might provide high secondary stability and successful osseointegration.
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http://dx.doi.org/10.5051/jpis.2105720286 | DOI Listing |
Mater Today Bio
February 2025
Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, Shanxi, China.
Bone defects caused by trauma, infection, or tumors present a major clinical challenge. Titanium (Ti) implants are widely used due to their excellent mechanical properties and biocompatibility; however, their high elastic modulus, low surface bioactivity, and susceptibility to infection hinder osseointegration and increase failure rates. There is an increasing demand for implants that can resist bacterial infection while promoting osseointegration.
View Article and Find Full Text PDFNatl J Maxillofac Surg
November 2024
Department of Oral and Maxillofacial Surgery, Hospital Universitario La Paz, Paseo de la Castellana, Madrid, Spain.
The anatomical location of certain lesions can be a difficulty when locating them intraoperatively. The use of surgical navigation allows anatomical structures to be located with great precision. However, there are technical difficulties with its use in mandibular surgery.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Foshan Clinical Medical School of Guangzhou University of Chinese Medicine, Guangdong Province, Foshan 528031, China. Electronic address:
Due to the limited ability to self-repair, the regeneration of bone critical-sized defects (CSD) is a significant challenge. Bone tissue engineering scaffolds are considered promising candidates for CSD repair, but low cell infiltration efficiency and a lack of nutrients greatly restrict bone regeneration abilities. Herein, we developed a dynamic culturing of large biomimetic bone scaffolds, PCL/GelMA@cells that combining 3D printed polycaprolactone (PCL) multi-channel cylinder with gelatin methacryloyl (GelMA) encapsulated with bone marrow mesenchymal stem cells (BMSCs) and rat aortic endothelial cells (RAECs).
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
January 2025
Center of Stomatological, The Second Hospital, Cheeloo College of Medicine, Shandong University, 250033, PR China; Jinan Key Laboratory of Oral Materials, Jinan, 250033, PR China. Electronic address:
A method is proposed for 3D printing and enhancing the surface bioactivity of zirconia ceramic anchor screws, specifically tailored for temporomandibular joint disc reduction surgery. Initially, the challenge posed by the brittleness and processing difficulties of fine ceramic anchor screws was addressed through the application of SLA-3D printing technology. This allowed for an exploration of the forming accuracy and biomechanical properties of the printed anchor screws.
View Article and Find Full Text PDFActa Biomater
January 2025
Central laboratory of Liaocheng People's Hospital, Liaocheng, Shandong, 252000, China. Electronic address:
Peripheral nerve injury (PNI) as a common clinical issue that presents significant challenges for repair. Factors such as donor site morbidity from autologous transplantation, slow recovery of long-distance nerve damage, and deficiencies in local cytokines and extracellular matrix contribute to the complexity of effective PNI treatment. It is extremely urgent to develop functional nerve guidance conduits (NGCs) as substitutes for nerve autografts.
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