AI Article Synopsis
- - The study investigates the impact of maternal colonization of specific species during pregnancy on the neurodevelopment of preterm infants born before 30 weeks of gestation.
- - In a cohort of 254 preterm infants, only 12.6% were exposed to maternal colonization, showing no significant difference in overall developmental scores at 24 months but poorer locomotor abilities in the exposed group.
- - Despite similar rates of cognitive and motor impairments between the two groups, the exposed infants had lower scores specifically in locomotor skills, indicating potential negative effects of maternal colonization on movement development.
Article Abstract
Introduction: (.) and (.) species have been related to pregnancy complications (including preterm birth) and worse neonatal outcomes. The aim of our work is to evaluate neurodevelopmental outcomes in preterm infants born to mothers with / colonization during pregnancy.
Methods: Preterm infants with gestational age (GA) of ≤ 30 weeks were included in a retrospective follow-up study. To evaluate the effects of maternal vaginal colonization, we divided preterm infants into two groups: exposed and unexposed infants. All infants were assessed at 24 ± 3 months of age using Griffith's Mental Developmental Scales (GMDS).
Results: Among 254 preterm infants, only 32 infants (12.6%) were exposed to U. /M. colonization during pregnancy. Exposed infants and unexposed ones had a similar Griffith's Developmental Quotient (106 ± 27.2 vs. 108.9 ± 19.5, respectively), without significant differences ( = 0.46). However, exposed infants had a significantly poorer outcome than their unexposed peers in terms of locomotor abilities (100.7 ± 28.3 exposed vs. 111.5 ± 26.1 unexposed, = 0.03).
Conclusion: For visual and hearing impairment, exposed and unexposed infants had similar incidences of cognitive and motor impairment. However, exposed infants had significantly lower locomotor scores than unexposed peers.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420904 | PMC |
| http://dx.doi.org/10.3389/fped.2022.893812 | DOI Listing |
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