Granuloma Annulare Mimicking Squamous Cell Carcinoma.

Cureus

Mohs and Complex Facial Reconstructive Surgery, Epiphany Dermatology, Rockwall, USA.

Published: July 2022

Misdiagnosing granuloma annulare (GA) for a malignant process can lead to unnecessary and costly treatment avenues for the patient. Thus, it is salient for surgeons to independently evaluate a patient's clinical and histopathologic presentation before proceeding with surgery. We present a case of a 67-year-old male with a biopsy-proven squamous cell carcinoma (SCC) on the dorsal hand who presented for Mohs micrographic surgery (MMS). At this time, the surgeon noticed the histopathologic diagnosis did not match the patient's clinical appearance. GA was diagnosed following a repeat biopsy of the lesion, which prevented an unnecessary Mohs procedure. We present this case primarily to highlight the importance of clinicopathologic correlation by the surgeon when a patient is referred for surgery.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9417919PMC
http://dx.doi.org/10.7759/cureus.27372DOI Listing

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Article Synopsis
  • Granuloma annulare (GA) is a non-infectious skin condition that can become widespread in some patients; this study focused on those with disseminated GA in a German hospital.
  • A total of 239 patients were studied, with 33 having confirmed disseminated GA, predominantly affecting women around the age of 57, and many reporting little to no symptoms.
  • Treatment options included glucocorticoids and phototherapy, but only a small percentage achieved remission, highlighting the need for more effective clinical trials for new therapies.
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Granuloma annulare (GA) is an idiopathic inflammatory skin condition with a chronic and unpredictable course. Although localized GA is usually cleared with topical or systemic corticosteroids, generalized GA is often difficult to treat owing to the lack of treatment options and recurrence with treatment. Recent evidence has helped to elucidate the etiology behind GA, with growing confirmation for the use of JAK inhibitors as a possible treatment for GA.

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Generalized granuloma annulare in a patient with human immunodeficiency virus infection.

Am J Med

December 2024

Department of Dermatology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan. Electronic address:

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Granuloma Annulare of the Palms in a Patient on Ribociclib for Metastatic Breast Cancer.

Cureus

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Dermatology, North Branch Dermatology, Chicago, USA.

Granuloma annulare (GA) is a benign inflammatory skin condition that most commonly presents on the dorsal surfaces of the hands and feet. The etiology of GA is unknown; however, it has been associated with multiple triggers, including malignancy and targeted cancer therapy drugs. This case report describes a 66-year-old female with metastatic breast cancer on ribociclib who presented with painful, erythematous papules on the palmar surfaces of the hands.

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