Genome Sequence of a Microvirus Recovered from Wastewater in Arizona, USA, in October 2020, Encodes a Previously Undescribed DNA-Binding Protein.

Abriana Smith Nicole Kaiser Allan Yanez Tyler Perleberg Amir Elyaderani Peter Skidmore Sangeet Adhikari Erin M Driver Rolf U Halden Arvind Varsani Matthew Scotch Temitope O C Faleye

Microbiol Resour Announc

Biodesign Center for Environmental Health Engineering, Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

Published: October 2022

The genome of Microvirus-AZ-2020, found in Arizona wastewater in October 2020, has been analyzed and documented.
It belongs to a certain subfamily and contains six open reading frames (ORFs), which are parts of the DNA that can be translated into proteins.
An analysis indicates that one of these ORFs is a hypothetical one that might encode a new type of DNA-binding protein not previously identified.

We describe the genome of Microvirus-AZ-2020, which was identified from wastewater in Arizona, USA, in October 2020. Microvirus-AZ-2020 belongs to subfamily and contains six (five known and one hypothetical) open reading frames (ORFs), each with >40 codons. HHPred analysis and Colabfold structure prediction suggest that the hypothetical ORF encodes a previously undescribed putative DNA-binding protein.

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584320	PMC
http://dx.doi.org/10.1128/mra.00337-22	DOI Listing

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