AI Article Synopsis

  • Chitosan and its nanoparticles are gaining attention for their beneficial properties, including biocompatibility, biodegradability, and nontoxicity.
  • Despite numerous studies on chitosan, there is a lack of research on its pharmacological applications and drug delivery.
  • This work aims to summarize the physical, chemical, and biological properties of chitosan, detail the synthesis and characterization of its nanoparticles and nanocomposites, and explore recent advancements in their pharmaceutical applications.

Article Abstract

Due to their improved structural and functional properties as well as biocompatibility, biodegradability, and nontoxicity, chitosan and its nanoparticles are currently grasping the interest of researchers. Although numerous attempts have been made to apply chitosan and its derivatives to biological applications, few have reported in achieving its pharmacological and drug delivery. The goal of the current work is to provide a summary of the chitosan biopolymer's physical, chemical, and biological properties as well as its synthesis of nanoparticles and characterization of its modified nanocomposites. The drug delivery method and pharmaceutical applications of chitosan biopolymer and its modified nanocomposites are examined in further detail in this research. We will introduce also about the most current publications in this field of study as well as its recent expansion.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420383PMC
http://dx.doi.org/10.1016/j.heliyon.2022.e10196DOI Listing

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