Cerebral venous sinus thrombosis following Russell's viper (Daboia russelii) envenomation: A case report and review of the literature.

Toxicon

Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Medicine, Complutense University, Madrid, Spain. Electronic address:

Published: October 2022

AI Article Synopsis

  • Snakebite poses a significant public health risk, especially in tropical and subtropical rural areas, leading to serious complications like stroke and paralysis.
  • This case study highlights a previously healthy Indian woman who experienced cerebral venous sinus thrombosis after a Russell's viper bite, showcasing a rare cerebrovascular complication.
  • The patient was successfully treated with antivenom and enoxaparin, achieving full recovery without neurological deficits after three months.

Article Abstract

Snakebite is a life-threatening and often-neglected public health hazard with high chronic disability and mortality, mainly faced by rural communities in the tropics/subtropics. Stroke and neuromuscular paralysis are the most severe neurological complications. However, cerebral venous sinus thrombosis has rarely been reported among cerebrovascular complications. We report a previously healthy middle-aged Indian woman who developed cerebral venous sinus thrombosis preceded by features of disseminated bleeding diathesis following Russell's viper bite. The cerebral venous sinus thrombosis was diagnosed by magnetic resonance imaging. The patient responded well to treatment with antivenom and subcutaneous enoxaparin and had no demonstrable neurological deficits at three months of follow-up.

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http://dx.doi.org/10.1016/j.toxicon.2022.08.014DOI Listing

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