Antifouling and Antibacterial Surfaces Grafted with Sulfur-Containing Copolymers.

ACS Appl Mater Interfaces

Australian Institute for Bioengineering and Nanotechnology and ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, The University of Queensland, St Lucia, Queensland 4072, Australia.

Published: September 2022

AI Article Synopsis

  • Antifouling and antibacterial surfaces are crucial for various biomedical uses, as they prevent unwanted biological adhesion.
  • The study introduced a new photopolymerization method to create surfaces with sulfur-containing polymer-grafted materials that resist protein and macrophage adhesion.
  • These surfaces not only repel biological matter but also have antibacterial properties due to the ionization of sulfate monomers, making them significant for future biomedical applications.

Article Abstract

Antifouling and antibacterial surfaces that can prevent nonspecific biological adhesion are important to support a myriad of biomedical applications. In this study, we have used an innovative photopolymerization technology to develop sulfur-containing polymer-grafted antifouling and antibacterial surfaces. The relationship between the hydrophilic property and the capability to resist protein and macrophage adsorption of the surface copolymer brushes was investigated. The sulfide monomer incorporated into the surface copolymer brushes can be further ionized to carry positive charges and impart antibacterial activity, leading to surfaces with dual antifouling and antibacterial functions. We believe that the reported sulfur-containing polymer brushes can be considered an emerging and important polymer for antifouling and antibacterial applications.

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Source
http://dx.doi.org/10.1021/acsami.2c09698DOI Listing

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