Range anxiety is a primary concern among present-day electric vehicle (EV) owners, which could be curtailed by maximizing the driving range per charge or reducing the charging time of the lithium-ion battery (LIB) pack. Maximizing the driving range is a multifaceted task as charging-discharging the LIB up to 100% of its nominal capacity is limited by the cell chemistry (voltage window) and cell operating conditions. Our studies on commercial LiFePO/graphite cells show that a cycle life of 4320 is achieved at 4C rate with 80% SOC-100% DOD combination (12 min charging time), which is the highest among the works reported with this cell chemistry. Complete utilization of electrodes' lithium during cycling resulted in the lowest cycle life of 956. This study demonstrates LIB charging-discharging protocol enabling longer driving range with quicker charging times. Besides, it might endow promising possibilities of future EV LIB packs with reduced size/weight and high safety.
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http://dx.doi.org/10.1016/j.isci.2022.104831 | DOI Listing |
BMC Musculoskelet Disord
January 2025
Department of Health Sciences, Faculty of Medicine, Lund University, Box 117, Lund, 221 00, Sweden.
Background: Osteoarthritis (OA) often leads to pain and functional limitations, impacting work and daily life. Physical activity (PA) is an important part of the treatment. Wearable activity trackers (WATs) offer a novel approach to promote PA but could also aid in finding a sustainable PA level over time.
View Article and Find Full Text PDFNat Cell Biol
January 2025
Department of Biochemistry, University of Oxford, Oxford, UK.
Delays in mitosis trigger p53-dependent arrest in G1 of the next cell cycle, thus preventing repeated cycles of chromosome instability and aneuploidy. Here we show that MDM2, the p53 ubiquitin ligase, is a key component of the timer mechanism triggering G1 arrest in response to prolonged mitosis. This timer function arises due to the attenuation of protein synthesis in mitosis.
View Article and Find Full Text PDFNat Commun
January 2025
Center for Integrative Genomics, University of Lausanne, Faculty of Biology and Medicine, Lausanne, Switzerland.
The energetic demands of proliferating cells during tumorigenesis require close coordination between the cell cycle and metabolism. While CDK4 is known for its role in cell proliferation, its metabolic function in cancer, particularly in triple-negative breast cancer (TNBC), remains unclear. Our study, using genetic and pharmacological approaches, reveals that CDK4 inactivation only modestly impacts TNBC cell proliferation and tumor formation.
View Article and Find Full Text PDFAnal Chim Acta
January 2025
University Regensburg, Institute of Analytical Chemistry, Universitätsstrasse 31, 93053, Regensburg, Germany. Electronic address:
Background: The demand for lithium-ion cells in the automotive industry is rapidly growing due to the increasing electrification of the transportation sector. The electrolyte composition plays a critical role in determining the lifetime and performance of these large-format cells. Additionally, advancements in this field are leading to frequent changes in both electrode materials and electrolyte formulations.
View Article and Find Full Text PDFBrain Res Bull
January 2025
First Affiliated Hospital, Heilongjiang University of Chinese Medicine, 150040 Harbin, Heilongjiang, China. Electronic address:
Major depressive disorder (MDD) is a common mental disorder with chronic tendencies that seriously affect regular work, life, and study. However, its exact pathogenesis remains unclear. Patients with MDD experience systemic and localized impairments in glucose metabolism throughout the disease course, disrupting various processes such as glucose uptake, glycoprotein transport, glycolysis, the tricarboxylic acid cycle (TCA), and oxidative phosphorylation (OXPHOS).
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