Viscous streaming refers to the rectified, steady flows that emerge when a liquid oscillates around an immersed microfeature. Relevant to microfluidics, the resulting local, strong inertial effects allow manipulation of fluid and particles effectively, within short time scales and compact footprints. Nonetheless, practically, viscous streaming has been stymied by a narrow set of achievable flow topologies, limiting scope and application. Here, by moving away from classically employed microfeatures of uniform curvature, we experimentally show how multicurvature designs, computationally obtained, give rise, instead, to rich flow repertoires. The potential utility of these flows is then illustrated in compact, robust, and tunable devices for enhanced manipulation, filtering, and separation of both synthetic and biological particles. Overall, our mixed computational/experimental approach expands the scope of viscous streaming application, with opportunities in manufacturing, environment, health, and medicine, from particle self-assembly to microplastics removal.
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http://dx.doi.org/10.1073/pnas.2120538119 | DOI Listing |
Methods Mol Biol
December 2024
Division of Developmental Physiology, Institute for Genetic Medicine, Hokkaido University, Hokkaido, Japan.
Cytoplasmic streaming is the bulk flow of cytoplasm observed, not only in plants but also in animal oocytes and embryos. The flow of viscous fluid within the cytoplasm generates forces that re-arrange intracellular organelles, such as mitotic spindles and nuclei, to regulate cell growth, migration, and polarity. Cytoplasmic streaming is established by motor proteins and the viscoelastic cytoskeleton, including the actin filaments and microtubules.
View Article and Find Full Text PDFLangmuir
December 2024
School of Mechanical Engineering, Dalian University of Technology, Dalian 116024, China.
Langmuir
November 2024
Hydrodynamics and Thermal Multiphysics Laboratory (HTML), Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India.
We explore the intricate dynamics of imbibition by a viscoelastic electrolyte within an arbitrarily oriented, nonuniform microcapillary, while under the stimulus of external electromagnetic fields and internal electroviscous forces stemming from streaming potential. The microcapillary walls are envisaged to be tapered relative to each other, with the entire system inclined with respect to the horizontal plane. The rheological behavior of the electrolyte is characterized using the Phan-Thien-Tanner (PTT) model.
View Article and Find Full Text PDFSmall
November 2024
National Nanotechnology Research Center (UNAM)- Bilkent University, Cankaya-Ankara, 06800, Türkiye.
Liposomes are widely utilized in therapeutic nanosystems as promising drug carriers for cancer treatment, which requires a meticulous synthesis approach to control the nanoprecipitation process. Acoustofluidic platforms offer a favorable synthesis environment by providing robust agitation and rapid mixing. Here, a novel high-throughput acoustofluidic micromixer is presented for a solvent and solvent-free synthesis of ultra-small and size-tunable liposomes.
View Article and Find Full Text PDFJ Colloid Interface Sci
January 2025
Department of Mechanical Engineering, IIT Kharagpur, Kharagpur 721302, India; Advanced Technology Development Centre, IIT Kharagpur, Kharagpur 721302, India. Electronic address:
Hypothesis: Harnessing electrical energy from salinity gradients, particularly for powering micro and nanoscale devices, has become a focal point of recent research attention, due to its renewable and biocompatible nature. Much of the reported research in that direction revolves around optimizing the membrane architecture and the charge distribution to maximize the induced electric potential, with no particular emphasis on the fluid rheology. However, many of the modern miniature systems, typically the bio-inspired ones, concern fluids with complex rheological characteristics, where the results for Newtonian solvents may not trivially apply.
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