The SARS-CoV-2 pandemic put the entire healthcare sector under severe strain due to shortages of personal protection equipment. A large number of new filtering mask models were introduced on the market, claiming effectiveness that had undergone little or no objective and reliable verifications. Filter materials were tested against sodium chloride particles according to the EN149 §7.9.2 standard for particle penetration. Particle counters were used to measure the particle penetration of the filtering mask models, resolved over sizes in the range of 27-1000 nm. We report on the results for 86 different filtering mask models. The majority of the tested models showed <3% penetration, whereas almost one third (i.e., 27 of 86) of the models performed poorly. Interestingly, the poorest performing masks showed a tendency to have worse filtering effectiveness for larger particles than for smaller sized particles, following the opposite tendency of the best filtering masks. Almost one third of the filtering mask models tested failed the specified pass criteria as specified in the temporary EU COVID-19 standard. This fact, and the high health risks of COVID-19, highlights the need for independent testing.
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http://dx.doi.org/10.1089/apb.2020.0082 | DOI Listing |
PLoS One
December 2024
Department of Health Promotion, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.
During the COVID-19 pandemic, meatpacking workers were disproportionately affected by disease. Large outbreaks at meatpacking facilities resulted in loss of life and threatened the well-being of workers across the globe. Much work was done throughout the pandemic to understand and prevent these outbreaks.
View Article and Find Full Text PDFNucleic Acids Res
December 2024
Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA.
Single-nuclei RNA sequencing remains a challenge for many human tissues, as incomplete removal of background signal masks cell-type-specific signals and interferes with downstream analyses. Here, we present Quality Clustering (QClus), a droplet filtering algorithm targeted toward challenging samples. QClus uses additional metrics, such as cell-type-specific marker gene expression, to cluster nuclei and filter empty and highly contaminated droplets, providing reliable filtering of samples with varying number of nuclei and contamination levels.
View Article and Find Full Text PDFJ Occup Environ Hyg
December 2024
National Personal Protective Technology Laboratory, National Institute for Occupational Safety and Health, Pittsburgh, Pennsylvania.
Developing and overseeing Respiratory Protection Programs (RPPs) is crucial for ensuring effective respirator use among employees. To date, a gap exists in research that focuses on elastomeric half mask respirators (EHMRs) as the primary respirator in health delivery settings which would necessitate additional considerations in RPPs beyond the more common N95 filtering facepiece respirators. This paper presents lessons learned during a one-year impact evaluation with healthcare and first responder settings that received EHMRs from the Strategic National Stockpile in 2021 and 2022.
View Article and Find Full Text PDFComput Methods Programs Biomed
December 2024
Lab. of Biomedical Diagnostics, Eindhoven University of Technology, Eindhoven, The Netherlands.
Background And Objective: The integration of ultrafast Doppler imaging with singular value decomposition clutter filtering has demonstrated notable enhancements in flow measurement and Doppler sensitivity, surpassing conventional Doppler techniques. However, in the context of transthoracic coronary flow imaging, additional challenges arise due to factors such as the utilization of unfocused diverging waves, constraints in spatial and temporal resolution for achieving deep penetration, and rapid tissue motion. These challenges pose difficulties for ultrafast Doppler imaging and singular value decomposition in determining optimal tissue-blood (TB) and blood-noise (BN) thresholds, thereby limiting their ability to deliver high-contrast Doppler images.
View Article and Find Full Text PDFJ Hazard Mater
December 2024
College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science &Technology, Xi'an 710021, China. Electronic address:
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