: The emergence of wireless capsule endoscopy (WCE) has presented a viable non-invasive mean of identifying gastrointestinal diseases in the field of clinical gastroenterology. However, to overcome its extended time of manual inspection, a computer aided automatic detection system is getting vast popularity. In this case, major challenges are low resolution and lack of regional context in images extracted from WCE videos. : For tackling these challenges, in this paper a convolution neural network (CNN) based architecture, namely RAt-CapsNet, is proposed that reliably employs regional information and attention mechanism to classify abnormalities from WCE video data. The proposed RAt-CapsNet consists of two major pipelines: Compression Pipeline and Regional Correlative Pipeline. In the compression pipeline, an encoder module is designed using a Volumetric Attention Mechanism which provides 3D enhancement to feature maps using spatial domain condensation as well as channel-wise filtering for preserving relevant structural information of images. On the other hand, the regional correlative pipeline consists of Pyramid Feature Extractor which operates on image driven feature vectors to generalize and propagate local relationships of pixels from WCE abnormalities with respect to the normal healthy surrounding. The feature vectors generated by the pipelines are then accumulated to formulate a classification standpoint. : Promising computational accuracy of mean 98.51% in binary class and over 95.65% in multi-class are obtained through extensive experimentation on a highly unbalanced public dataset with over 47 thousand labelled. : This outcome in turn supports the efficacy of the proposed methodology as a noteworthy WCE abnormality detection as well as diagnostic system.
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http://dx.doi.org/10.1109/JTEHM.2022.3198819 | DOI Listing |
Arch Dermatol Res
January 2025
Department of Dermatology, Changhua Christian Hospital, Changhua, Taiwan.
Background: While several studies have suggested a connection between Metabolic Syndrome (MetS) and Hidradenitis Suppurativa (HS), a definitive analysis confirming the association between lipid abnormalities and HS based on actual lipid values is lacking. Previous research, using odds ratios from ICD codes, indicates links between elevated triglycerides and low high-density lipoprotein levels with HS. However, these findings may not fully represent real-life situations, as no comprehensive analysis using actual lipid measurements has been performed.
View Article and Find Full Text PDFLangmuir
January 2025
Materials Science and Technology Division, CSIR─National Institute for Interdisciplinary Science and Technology, Pappanamcode, Thiruvananthapuram 695019, Kerala, India.
Mercury contamination of the environment is extremely hazardous to human health because of its significant toxicity, especially in water. Biomass-derived fluorophores such as carbon dots (CDs) have emerged as eco-friendly and cost-effective alternative sensors that provide comparable efficacy while mitigating the environmental and economic drawbacks of conventional methods. In this work, we report the fabrication of a selective fluorescence-enhancing sensor based on sulfur-doped carbon dots (SCDs) using waste bamboo-derived cellulose and sodium thiosulfate as the soft base dopant, which actively complexes with mercury ions for detection.
View Article and Find Full Text PDFJ Hypertens
December 2024
Institute for Fetology, The First Affiliated Hospital of Soochow University, Jiangsu.
Background: Paternal preconception alcohol exposure affects fetal development; however, it is largely unknown about the influences on offspring vasculature and mechanisms.
Methods: Offspring born form paternal rats treated with alcohol or water before pregnant was raised until 3 months of age. Vessel tone of mesenteric arteries was detected using myograph system; whole-cell calcium channel current in smooth muscle cells was tested using patch-clamp; molecule expressions were detected with real-time PCR, western blotting, and Dihydroethidium (DHE); DNA methylations were determined using targeted bisulfate sequencing assay.
Vet Radiol Ultrasound
January 2025
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
A young, intact, female, American Bulldog was presented for hemorrhagic vaginal discharge. Anemia, thrombocytopenia, leukocytosis with neutrophilia, azotemia, and electrolyte disturbances were detected in the bloodwork. A urachal diverticulum with concurrent uterine distention was identified by ultrasonography and CT.
View Article and Find Full Text PDFHum Brain Mapp
January 2025
Center for MR Research, University Children's Hospital Zurich, Zurich, Switzerland.
The human brain connectome is characterized by the duality of highly modular structure and efficient integration, supporting information processing. Newborns with congenital heart disease (CHD), prematurity, or spina bifida aperta (SBA) constitute a population at risk for altered brain development and developmental delay (DD). We hypothesize that, independent of etiology, alterations of connectomic organization reflect neural circuitry impairments in cognitive DD.
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