As the old adage goes: practice makes perfect. Yet, the neural mechanisms by which rote repetition transforms a halting behavior into a fluid, effortless, and "automatic" action are not well understood. Here we consider the possibility that well-practiced motor sequences, which initially rely on higher-level decision-making circuits, become wholly specified in lower-level control circuits. We review studies informing this idea, discuss the constraints on such shift in control, and suggest approaches to pinpoint circuit-level changes associated with motor sequence learning.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11125547 | PMC |
| http://dx.doi.org/10.1016/j.conb.2022.102624 | DOI Listing |
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