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Axial Spondyloarthritis Clinical Research Year in Review: SPARTAN 2024 Annual Meeting Proceedings.
Curr Rheumatol Rep
January 2025
Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, USA.
Purpose Of Review: The purpose of this review is to highlight high impact clinical research in axial spondyloarthritis that was published between May 2023 and April 2024. These publications were presented at the SPARTAN annual meeting in May 2024.
Recent Findings: Three publications addressed the rate and predictors of radiographic progression in axial spondyloarthritis.
Correction: Consensus‑driven protocol for transanal irrigation in patients with low anterior resection syndrome and functional constipation.
Tech Coloproctol
January 2025
Surgical Department, Ostomy and Pelvic Floor Rehabilitation Center, Azienda Sanitaria Universitaria Friuli Centrale, Santa Maria della Misericordia, Udine, Italy.
Assessing live microbial therapeutic transmission.
Gut Microbes
December 2025
Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
The development of fecal microbiota transplantation and defined live biotherapeutic products for the treatment of human disease has been an empirically driven process yielding a notable success of approved drugs for the treatment of recurrent infection. Assessing the potential of this therapeutic modality in other indications with mixed clinical results would benefit from consistent quantitative frameworks to characterize drug potency and composition and to assess the impact of dose and composition on the frequency and duration of strain engraftment. Monitoring these drug properties and engraftment outcomes would help identify minimally sufficient sets of microbial strains to treat disease and provide insights into the intersection between microbial function and host physiology.
View Article and Find Full Text PDFEfficacy evaluation of a minimally invasive surgical procedure (oblique lateral interbody fusion) for lumbar spinal tuberculosis-retrospective cohort study.
Front Bioeng Biotechnol
December 2024
Department of Orthopaedics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Objective: In the current study, to demonstrate the advantages of oblique lateral interbody fusion (OLIF), we focused on the therapeutics for lumbar spinal tuberculosis with the comparison of three treatments, including anterior approach, posterior approach, and OLIF combined with posterior percutaneous pedicle screw fixation.
Methods: This study included patients with lumbar spinal tuberculosis from July 2015 to June 2018. We divided these patients into three groups: 35 patients underwent an anterior-only approach (Group A), 36 patients underwent a posterior-only approach (Group B), and 31 patients underwent OLIF combined with posterior percutaneous pedicle screw fixation (Group C).
Current concepts of fourth-generation minimally invasive and open hallux valgus surgery.
Bone Joint J
January 2025
King's Foot and Ankle Unit, King's College Hospital NHS Foundation Trust, London, UK.
Hallux valgus (HV) presents as a common forefoot deformity that causes problems with pain, mobility, footwear, and quality of life. The most common open correction used in the UK is the Scarf and Akin osteotomy, which has good clinical and radiological outcomes and high levels of patient satisfaction when used to treat a varying degrees of deformity. However, there are concerns regarding recurrence rates and long-term outcomes.
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