Background: Honey has broad spectrum antibacterial activity against clinically important organisms and may be suitable for treating superficial bacterial infections. However, very little data are available describing potential interactions between honey and other topically applied agents such as antiseptics or essential oils.
Methods: Interactions between pairs of antibacterial agents were investigated by performing checkerboard assays and determining the fractional inhibitory concentration indices (FICIs). Interactions between the two monofloral honeys marri (from Corymbia calophylla) and manuka, and the antiseptic agents benzalkonium chloride, chlorhexidine digluconate, silver (I) nitrate, tea tree oil, and Eucalyptus polybractea oil were investigated against Staphylococcus aureus ATCC® 43300 and Pseudomonas aeruginosa ATCC® 27853.
Results: Additive or indifferent interactions (FICI 0.5-2) were observed for all combinations against both organisms tested, with the exception of chlorhexidine and honey. Chlorhexidine and marri honey showed an antagonistic relationship against S. aureus (median FICI 2.00, range 1.25-4.83). Similarly, chlorhexidine and manuka honey showed antagonism against S. aureus (median FICI 2.33, range 2.00-2.67).
Conclusions: With the exception of chlorhexidine, these data indicate that honey does not interfere with the antimicrobial activity of the tested agents, and that honey may be suitable for combination therapy with other topically applied antibacterial agents for treating superficial bacterial infections.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9419324 | PMC |
| http://dx.doi.org/10.1186/s12906-022-03695-x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Changes in the Activities of Antioxidant Enzymes in the Fat Body and Hemolymph of L. Due to Pollen Monodiets.
Antioxidants (Basel)
January 2025
Department of Invertebrate Ecophysiology and Experimental Biology, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
The increasing prevalence of monocultures has reduced floral diversity, diminishing pollen diet variety for bees. This study examines the impact of monofloral pollen diets (hazel, rapeseed, pine, buckwheat, , goldenrod) on the antioxidant enzyme activities in the fat body from tergite 3, tergite 5, sternite, and hemolymph of honey bees. We show that pollen from plants such as rapeseed, , buckwheat, and goldenrod (rich in phenolic compounds and flavonoids) increases the activities of SOD, CAT, GST, and GPx in the fat body and hemolymph compared to the control group.
View Article and Find Full Text PDFDetection of glyphosate, glufosinate, and their metabolites in multi-floral honey for food safety.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
January 2025
Department of Veterinary Medicine and Animal Science (DIVAS), University of Milan, Lodi, Italy.
Beehives can accumulate environmental contaminants as bees gather pollen, propolis, and water from their surroundings, contaminating hive products like honey. Moreover, in multifloral environments, bees can interact with plants treated with different pesticides, often causing higher pesticides concentrations in multi-floral honey than in mono-floral varieties. Glyphosate and glufosinate are both widely used herbicides.
View Article and Find Full Text PDFInvestigating the influence of diet diversity on infection outcomes in a bumble bee () and microsporidian () host-pathogen system.
Front Insect Sci
August 2023
School of Biological Sciences, Illinois State University, Normal, IL, United States.
Diet can have an array of both direct and indirect effects on an organism's health and fitness, which can influence the outcomes of host-pathogen interactions. Land use changes, which could impact diet quantity and quality, have imposed foraging stress on important natural and agricultural pollinators. Diet related stress could exacerbate existing negative impacts of pathogen infection.
View Article and Find Full Text PDFBiochemical characterization of Euphorbia resinifera floral cyathia.
J Plant Physiol
February 2024
Department of Biology, Utah State University, Logan, UT, 84321-5305, USA. Electronic address:
Article Synopsis
- Euphorbia resinifera is a Moroccan plant known for its poisonous latex but produces beneficial nectar from its cyathia, which honey bees use to make honey.
- The cyathia are rich in primary metabolites like sugars, amino acids, and vitamins, supporting bee nutrition and honey production.
- Additionally, these structures synthesize various beneficial compounds, including antioxidants, enhancing their role in both pollinator attraction and traditional medicine applications.
Quality of bee pollen submitted to drying, pasteurization, and high-pressure processing - A comparative approach.
Food Res Int
August 2023
Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, 5300-252 Bragança, Portugal; Laboratório para a Sustentabilidade e Tecnologia em Regiões de Montanha, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Bee Pollen is a valuable and useful natural food product that can be used for different purposes, among which medical ones. This matrix is deemed a superfood because of its chemical composition, which is rich in nutrients and possesses significant bioactivities, including antioxidant and microbiological properties. Nevertheless, the storage conditions and processing methods must be optimized to maintain their properties and maximise their application.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!