AI Article Synopsis
- The Indonesian government rolled out a COVID-19 vaccination program using the Moderna mRNA vaccine to combat rising cases, despite concerns over potential side effects, including neurological issues.
- A 39-year-old woman with a history of high blood pressure experienced behavioral and cognitive changes shortly after receiving the vaccine, showing symptoms of encephalopathy.
- This case highlights the need for awareness of encephalopathy as a possible adverse effect of the Moderna vaccine, marking a first reported instance in Indonesia.
Article Abstract
Background: Due to a rising number of COVID-19 cases, the Indonesian government implemented public health programs to lower the rate. Since January 2021, one of the government's primary policies has been the COVID-19 immunization program. Recently, the Moderna messenger ribonucleic acid (mRNA) vaccine is one of the COVID-19 vaccines used in Indonesia. Based on some research, Moderna has possible side effects throughout the body, including neurological symptoms.
Case Presentation: We describe a 39-year-old female with uncontrolled hypertension who showed behavioral change, communication difficulty, social withdrawal, and a confused state within 7 days from getting her first dose of the Moderna vaccine. The patient had a history of febrile convulsion in childhood. An increase of neutrophil-to-lymphocyte ratio (16.9) and C-reactive protein level (31.75 mg/L) indicates ongoing inflammation. Head CT scan shows no abnormalities. She received ceftriaxone, citicoline, and methylprednisolone. The patient was discharged on the seventh day and completely recovered 1 week later. This study is the first case report of encephalopathy following the administration of the Moderna COVID-19 vaccine reported in Indonesia up to our knowledge.
Conclusion: Encephalopathy related to the Moderna COVID-19 vaccine should be acknowledged as an adverse effect of the Moderna COVID-19 vaccine.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412800 | PMC |
| http://dx.doi.org/10.1186/s12883-022-02834-8 | DOI Listing |
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