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Effects of Combined Intrathecal Mesenchymal Stem Cells and Schwann Cells Transplantation on Neuropathic Pain in Complete Spinal Cord Injury: A Phase II Randomized Active-Controlled Trial.
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Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Neuropathic pain is a debilitating complication following spinal cord injury (SCI). Currently, effective treatments for SCI-induced neuropathic pain are highly lacking. This clinical trial aimed to investigate the efficacy of combined intrathecal injection of Schwann cells (SCs) and bone marrow-derived mesenchymal stem cells (BMSCs) in improving SCI-induced neuropathic pain.
View Article and Find Full Text PDFMELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies.
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Background: Radiofrequency ablation (RFA) is an efficient treatment with unlimited potential for liver cancer that can effectively reduce patient mortality. Understanding the biological process related with RFA treatment is important for improving treatment strategy. This study aimed to identify the critical targets for regulating the efficacy of RFA.
View Article and Find Full Text PDFDecoding airway granulogenesis in children: unveiling risk factors for tracheobronchial foreign body aspiration and complications.
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Children's Respiratory Department, Quanzhou Maternity and Children's Hospital, Quanzhou, Fujian, 362000, China.
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Ultrasound tissue characterization and function of Achilles tendon in psoriatic arthritis patients: a cross-sectional study.
Eur J Phys Rehabil Med
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Division of Physical Medicine and Rehabilitation, Department of Surgical Sciences, University of Turin, Turin, Italy -
Background: The Achilles tendon is one of the most frequent sites of tendinopathy in both healthy and pathological subjects. An innovative approach for the quantitative assessment of the Achilles tendon structure, named Ultrasound Tissue Characterization (UTC), has recently been developed. However, no previous study performed the UTC-based assessment of the tendon structure in rheumatologic patients affected by insertional Achilles tendinopathy.
View Article and Find Full Text PDFTowards device technologies non-invasive to our daily lives.
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Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA.
Recent advances in non-invasive technologies have shown disruptive potential for biomedical applications. However, while surgically non-invasive, they may introduce other types of limitations which interfere with the patient’s quality of life, from impracticalities and discomfort in daily life to social stigma.
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