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Brain Sci
November 2024
Department of Computer Science, Yobe State University, Damaturu 600213, Nigeria.
Background/objectives: Magnetic Resonance Imaging (MRI) plays a vital role in brain tumor diagnosis by providing clear visualization of soft tissues without the use of ionizing radiation. Given the increasing incidence of brain tumors, there is an urgent need for reliable diagnostic tools, as misdiagnoses can lead to harmful treatment decisions and poor outcomes. While machine learning has significantly advanced medical diagnostics, achieving both high accuracy and computational efficiency remains a critical challenge.
View Article and Find Full Text PDFPituitary
December 2024
Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Adrenocorticotropin (ACTH)-dependent Cushing's syndrome can arise from a pituitary tumour (Cushing's disease) or an ectopic ACTH-secreting tumour, making precise differentiation essential for effective treatment. Bilateral inferior petrosal sinus sampling (BIPSS) is the gold standard for this differentiation, but false-negative results can limit its accuracy. Adding prolactin (PRL) measurement to BIPSS has been proposed to improve diagnostic precision.
View Article and Find Full Text PDFNeurosurg Rev
December 2024
Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South Fourth Ring West Road, Beijing, 100070, China.
Although craniopharyngiomas are rare benign brain tumors primarily managed by surgery, they are often burdened by a poor prognosis due to tumor recurrence and long-term morbidity. In recent years, BRAF-targeted therapy has been promising, showing potential as an adjuvant or neoadjuvant approach. Therefore, we aim to develop and validate a radiomics nomogram for preoperative prediction of BRAF mutation in craniopharyngiomas.
View Article and Find Full Text PDFDigit Health
December 2024
School of Computer Science & Engineering (SCOPE), VIT-AP University, Amaravati, Andhra Pradesh, India.
Objective: Brain tumors are abnormal growths of brain cells that are typically diagnosed via magnetic resonance imaging (MRI), which helps to discriminate between malignant and benign tumors. Using MRI image analysis, tumor sites have been identified and classified into four distinct tumor categories: meningioma, glioma, not tumor, and pituitary. If a brain tumor is not detected in its early stages, it could progress to a severe level or cause death.
View Article and Find Full Text PDFRen Fail
December 2024
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Key Laboratory of Nephrology, Ministry of Health of China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China.
Background: Resistance to thyroid hormone shows underlying mechanical link with chronic kidney disease (CKD) and is prevalent in CKD population. However, whether it attributes to mortality risk among CKD population is unknown. This study aimed to examine the association of thyroid hormone resistance (THR) with all-cause and cause-specific mortality among CKD individuals.
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