AI Article Synopsis
- An electrochemical cell with graphite rods and a specific electrolyte was used to synthesize graphene (EGr) by applying a 7 V bias for 3 hours.
- After the synthesis, characterization techniques like SEM, XRD, and FTIR were employed to analyze the structure and morphology of the graphene material, which was then used to modify a glassy carbon electrode (EGr/GC).
- The EGr/GC electrode demonstrated significantly improved electrochemical performance for detecting azithromycin (AZT), showing a higher oxidation peak at a lower potential and three times greater sensitivity compared to the bare GC electrode.
Article Abstract
An electrochemical cell containing two graphite rods was filled with the appropriate electrolyte (0.2 M ammonia + 0.2 M ammonium sulphate) and connected to the exfoliation system to synthesize graphene (EGr). A bias of 7 V was applied between the anode and cathode for 3 h. After synthesis, the morphology and structure of the sample was characterized by SEM, XRD, and FTIR techniques. The material was deposited onto the surface of a glassy carbon (GC) electrode (EGr/GC) and employed for the electrochemical detection of azithromycin (AZT). The DPV signals recorded in pH 5 acetate containing 6 × 10 M AZT revealed significant differences between the GC and EGr/GC electrodes. For EGr/GC, the oxidation peak was higher and appeared at lower potential (+1.12 V) compared with that of bare GC (+1.35 V). The linear range for AZT obtained with the EGr/GC electrode was very wide, 10-10 M, the sensitivity was 0.68 A/M, and the detection limit was 3.03 × 10 M. It is important to mention that the sensitivity of EGr/GC was three times higher than that of bare GC (0.23 A/M), proving the advantages of using graphene-modified electrodes in the electrochemical detection of AZT.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413463 | PMC |
| http://dx.doi.org/10.3390/s22166181 | DOI Listing |
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