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Epigenetic Regulation of Optic Nerve Development, Protection, and Repair. | LitMetric

Epigenetic Regulation of Optic Nerve Development, Protection, and Repair.

Int J Mol Sci

Department of Ophthalmology, Schepens Eye Research Institute of Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.

Published: August 2022

AI Article Synopsis

  • Epigenetic factors play a crucial role in the development and functionality of tissues, including the optic nerve, and influence their response to diseases.
  • This review highlights various epigenetic regulators and their molecular mechanisms that specifically impact the optic nerve.
  • Understanding these regulatory processes could lead to new therapeutic strategies for protecting, repairing, and regenerating the optic nerve.

Article Abstract

Epigenetic factors are known to influence tissue development, functionality, and their response to pathophysiology. This review will focus on different types of epigenetic regulators and their associated molecular apparatus that affect the optic nerve. A comprehensive understanding of epigenetic regulation in optic nerve development and homeostasis will help us unravel novel molecular pathways and pave the way to design blueprints for effective therapeutics to address optic nerve protection, repair, and regeneration.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408916PMC
http://dx.doi.org/10.3390/ijms23168927DOI Listing

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