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Background: Cold agglutinin disease (CAD) is an autoimmune hemolytic anemia that induces blood coagulation and hemolysis upon exposure to cold temperatures. Strict temperature control is essential to mitigate these effects, especially during surgical procedures where hypothermia is possible.

Case Presentation: A 57-year-old male, 165 cm and 72 kg, diagnosed with CAD, underwent cerebral vascular anastomosis.

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Autoimmune hemolytic anemia (AIHA) secondary to mediastinal teratoma is a very rare clinical entity. They can be primary or secondary to any infections, malignancy, etc. Yet at times, there could be a delay in the diagnosis.

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Paravalvular leak (PVL) following transcatheter aortic valve replacement (TAVR) is an established complication, albeit rarely associated with hemolytic anemia. This report details 3 cases of significant hemolytic anemia attributed to TAVR-induced PVL, each with distinct clinical presentations and manifestations. These cases underscore the diverse and occasionally subtle clinical presentation of aortic PVL-associated hemolytic anemia.

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With the use of Anti-D prophylaxis for rhesus D-negative pregnant women, other Rh and non-Rh allo-antibodies have become relatively more important. The index case reports severe hemolytic disease of the newborn due to anti-E antibody in a full-term baby boy born to a COVID-19-positive mother. The antibody screening of the mother performed during Booking of pregnancy at 9 week of gestation was negative.

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A case report on weak subgroup of A: A.

Asian J Transfus Sci

May 2023

Department of Transfusion Medicine and Blood Bank, AIIMS, Raipur, Chhattisgarh, India.

A end is a weak subgroup of Blood group A, found rarely in general population, not detected by routine forward and reverse blood grouping, detected by Adsorption/Elution technique along with saliva testing for A, B and H antigens. Although it is subgroup of A but it lacks A antigen in saliva and contains only H antigen. A 25y/M was accepted for blood donation and showed weak/mf reaction with anti-A in forward grouping.

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