The SARS-CoV-2 virus has proliferated around the world and caused panic to all people as it claimed many lives. Since COVID-19 is highly contagious and spreads quickly, an early diagnosis is essential. Identifying the COVID-19 patients' mortality risk factors is essential for reducing this risk among infected individuals. For the timely examination of large datasets, new computing approaches must be created. Many machine learning (ML) techniques have been developed to predict the mortality risk factors and severity for COVID-19 patients. Contrary to expectations, deep learning approaches as well as ML algorithms have not been widely applied in predicting the mortality and severity from COVID-19. Furthermore, the accuracy achieved by ML algorithms is less than the anticipated values. In this work, three supervised deep learning predictive models are utilized to predict the mortality risk and severity for COVID-19 patients. The first one, which we refer to as CV-CNN, is built using a convolutional neural network (CNN); it is trained using a clinical dataset of 12,020 patients and is based on the 10-fold cross-validation (CV) approach for training and validation. The second predictive model, which we refer to as CV-LSTM + CNN, is developed by combining the long short-term memory (LSTM) approach with a CNN model. It is also trained using the clinical dataset based on the 10-fold CV approach for training and validation. The first two predictive models use the clinical dataset in its original CSV form. The last one, which we refer to as IMG-CNN, is a CNN model and is trained alternatively using the converted images of the clinical dataset, where each image corresponds to a data row from the original clinical dataset. The experimental results revealed that the IMG-CNN predictive model outperforms the other two with an average accuracy of 94.14%, a precision of 100%, a recall of 91.0%, a specificity of 100%, an F1-score of 95.3%, an AUC of 93.6%, and a loss of 0.22.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406405 | PMC |
http://dx.doi.org/10.3390/diagnostics12081847 | DOI Listing |
NPJ Digit Med
January 2025
Graduate School of Data Science, Seoul National University, Seoul, Republic of Korea.
Polysomnography (PSG) is crucial for diagnosing sleep disorders, but manual scoring of PSG is time-consuming and subjective, leading to high variability. While machine-learning models have improved PSG scoring, their clinical use is hindered by the 'black-box' nature. In this study, we present SleepXViT, an automatic sleep staging system using Vision Transformer (ViT) that provides intuitive, consistent explanations by mimicking human 'visual scoring'.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Anesthesiology and Surgical Intensive Care Unit, Kunming Children's Hospital, Kunming, Yunnan, China.
Metabolic syndrome (Mets) in adolescents is a growing public health issue linked to obesity, hypertension, and insulin resistance, increasing risks of cardiovascular disease and mental health problems. Early detection and intervention are crucial but often hindered by complex diagnostic requirements. This study aims to develop a predictive model using NHANES data, excluding biochemical indicators, to provide a simple, cost-effective tool for large-scale, non-medical screening and early prevention of adolescent MetS.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, People's Republic of China.
Benign prostatic hyperplasia (BPH) is a prevalent urinary system disorder. Despite evidence of a significant genetic component from previous studies, the specific pathogenic genes and biological mechanisms are still largely unknown. The study utilized the FinnGen R10 dataset, encompassing 177,901 individuals (36,601 cases and 141,300 controls), and the GTEx v8 EQTLs files to conduct single-tissue and cross-tissue transcriptome-wide association studies (TWAS).
View Article and Find Full Text PDFSci Rep
January 2025
Division of Pancreatic Surgery, Department of General Surgery, Qilu Hospital, Shandong University, Jinan, 250012, China.
Previous studies have found that dyslipidemia is a risk factor for pancreatic cancer (PC), and that lipid-lowering drugs may reduce the risk of PC. However, it is not clear whether dyslipidemia causes PC. The Mendelian randomization (MR) study aimed to investigate the causal role of lipid traits in pancreatic cancer and to assess the potential impact of lipid-lowering drug targets on pancreatic cancer.
View Article and Find Full Text PDFSci Rep
January 2025
Ministry of Higher Education, Mataria Technical College, Cairo, 11718, Egypt.
The current work introduces the hybrid ensemble framework for the detection and segmentation of colorectal cancer. This framework will incorporate both supervised classification and unsupervised clustering methods to present more understandable and accurate diagnostic results. The method entails several steps with CNN models: ADa-22 and AD-22, transformer networks, and an SVM classifier, all inbuilt.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!