In veterinary medicine, calcinosis circumscripta is a morphological diagnosis for which the cause may be known or idiopathic. The aetiology of the lesion must be investigated because the nature of the underlying disease process will dictate appropriate treatment. We present a case of oral calcinosis circumscripta in a cat caused by a wasp sting and associated with moderate unilateral facial oedema. Following corticosteroid therapy and oedema resolution, hyperaemic, circular, firm, elevated lesions were observed on the buccal mucosa and evolved into whitish, slightly elevated multifocal plaques with an irregular surface. As antibiotic and corticosteroid therapy was ineffective, an excisional biopsy was performed after 6 months of lesion development and a diagnosis of calcinosis circumscripta of dystrophic aetiology was made. To our knowledge, this is the first report of calcinosis circumscripta in association with an insect sting in an animal. Insect stings should be included in the differential diagnosis of calcinosis circumscripta in cats.
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http://dx.doi.org/10.1016/j.jcpa.2022.06.001 | DOI Listing |
JFMS Open Rep
August 2024
Veterinary Specialists of Sydney, Miranda, NSW, Australia.
Case Summary: A 6-month-old male entire domestic shorthair cat presented for presumptive myopathy that was non-responsive to antiprotozoal therapy. Clinical features included marked macroglossia, dysphagia, regurgitation, truncal muscle hypertrophy, pelvic limb gait abnormalities and megaoesophagus. Relevant diagnostics included serial creatine kinase activity, cardiac troponin I, fluoroscopic swallow study and routine muscle histopathology.
View Article and Find Full Text PDFDis Aquat Organ
October 2023
Department of Comparative Biomedicine and Food Science, University of Padova, Legnaro, 35020, Italy.
This report presents an intriguing case of a mineralized lesion resembling calcinosis circumscripta observed in the caudal peduncle of a wels catfish, housed in a public aquarium in northern Italy. The investigation encompasses a comprehensive analysis of various aspects, including clinical presentation, diagnostic imaging, as well as gross and microscopic pathology, and immunohistochemistry. Histopathology, in particular, highlighted a severe focally extensive granulomatous reaction, confirmed by dense histiocytic inflammatory infiltrates and the massive presence of multinucleated foreign body type giant cells localized around lakes and aggregates of mineralized material.
View Article and Find Full Text PDFSA J Radiol
September 2023
Department of Radiology, Greys Hospital, Pietermaritzburg, South Africa.
Unlabelled: Calcinosis circumscripta involving the breasts usually hints at an underlying systemic cause, most commonly connective tissue disorders such as scleroderma or dermatomyositis. Localised scleroderma, also known as morphoea, is not usually associated with the systemic anomalies affecting the lungs and gastrointestinal system, but does manifest as calcified dermal and subdermal sclerotic plaques. Histological confirmation with skin biopsy is diagnostic.
View Article and Find Full Text PDFJ Small Anim Pract
July 2023
Anderson Moores Veterinary Specialists, Bunstead Barns, Poles Lane, Hursley, Winchester, Hampshire, SO21 2LL, UK.
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