AI Article Synopsis
- A novel A-D-A small-molecule photosensitizer called DPTTIC and a dual PEG-functionalized pillararene (WP5-8C-2PEG) were synthesized to create new DPTTIC nanoparticles.
- Under 980 nm laser light, these nanoparticles demonstrated effective performance in photothermal and photodynamic therapies for cancer treatment.
- The DPTTIC nanoparticles showed the ability to absorb near-infrared light (NIR II), enabling mild-temperature therapeutic applications.
Article Abstract
In the current work, we synthesized an A-D-A smallmolecule photosensitizer, denoted as DPTTIC, and a dual PEG-functionalized pillararene, denoted as WP5-8C-2PEG, and used them to construct novel DPTTIC nanoparticles (NPs) displaying NIR II absorption. Under 980 nm-wavelength laser irradiation, DPTTIC NPs performed well in mild-temperature photothermal and type I & II photodynamic anti-tumor therapy.
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| http://dx.doi.org/10.1039/d2cc03248a | DOI Listing |
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