Purpose: To perform a literature review on hyperbaric oxygen (HBO2) therapy as a treatment for exercise-induced muscle damage (EIMD).
Methods: PubMed, Web of Science and Google Scholar were searched for articles related to HBO2 therapy as a treatment for exercise-induced muscle damage. Inclusion criteria included HBO2 therapy as the primary intervention to treat EIMD. Articles used in this review ranged from 1995-2021.
Conclusion: Current literature on the effectiveness of HBO2 therapy to treat EIMD is mixed. Early and frequent treatments seem to be important factors when it comes to the success of HBO2 therapy. Additional research is needed to determine if HBO2 therapy has potential to treat more severe forms of EIMD and the role HBO2 therapy has on inflammation and satellite cell function after EIMD.
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Front Neurol
December 2024
Department of Rehabilitation, Kunming Children's Hospital, Kunming Medical University, Kunming, Yunnan, China.
Background: Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder characterized by inattention, impulsivity, and hyperactivity. With the continuous development of neuromodulation technology, Repetitive Transcranial Magnetic Stimulation (rTMS) has emerged as a potential non-invasive treatment for ADHD. However, there is a lack of research on the mechanism of rTMS for ADHD.
View Article and Find Full Text PDFBehav Brain Res
December 2024
Department of Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, A. Deusinglaan 1, Groningen 9713 AV, the Netherlands. Electronic address:
Background: Whole-body vibration (WBV) training has emerged as an alternative exercise modality for individuals unable to participate in regular physical activity. While previous studies demonstrated positive effects of WBV on physical outcomes, its impact on cognition remains relatively unexplored, despite studies suggesting cognitive benefits. This study aims to investigate the cortical activation patterns in the primary somatosensory cortex (S1) and dorsolateral prefrontal cortex (DLPFC) during WBV and a subsequent cognitive task.
View Article and Find Full Text PDFJ Biomed Opt
February 2025
Université Claude Bernard Lyon 1, Univ Lyon, INSA-Lyon, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR, Lyon, France.
Significance: Intraoperative optical imaging is a localization technique for the functional areas of the human brain cortex during neurosurgical procedures. These areas can be assessed by monitoring cerebral hemodynamics and metabolism. Robust quantification of these biomarkers is complicated to perform during neurosurgery due to the critical context of the operating room.
View Article and Find Full Text PDFExp Hematol
November 2024
Forma Therapeutics, Inc., Watertown, MA.
Anemia in patients with sickle cell disease (SCD) increases 2,3-diphosphoglycerate (2,3-DPG), decreasing hemoglobin-oxygen (HbO) affinity to improve oxygen offloading and promote hemoglobin polymerization (sickling) of red blood cells (RBCs). We report the discovery of FT-4202, an investigational, selective pyruvate kinase type-R (PKR) activator with a multimodal mechanism of action and potential to increase ATP and decrease 2,3-DPG, resulting in increased HbO affinity, decreased Hb polymerization, and improved RBC health. FT-4202 was identified via structure-enabled lead optimization medicinal chemistry using X-ray crystallography, molecular modeling, and thermal shift assays.
View Article and Find Full Text PDFActa Psychol (Amst)
November 2024
Dept. of Occupational Therapy, College of Software and Digital Healthcare Convergence, Yonsei University, South Korea. Electronic address:
Previous research has extensively explored cognitive and neural deficits in clinically diagnosed depression, but the early stages of depression, where symptoms do not meet clinical thresholds, are less explored. This study investigated neurocognitive markers in individuals with non-clinical depression. The study assessed working memory (WM) performance and hemodynamic responses of prefrontal cortex (PFC) in 30 individuals with non-clinical depression and 41 healthy controls using two-back tasks with four stimulus types: numbers, letters, shapes, and emotional facial expressions.
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