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| http://dx.doi.org/10.2340/actadv.v102.2522 | DOI Listing |
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Ocular Involvement in Systemic Sclerosis: Updated Review and New Insights on Microvascular Impairment.
Ocul Immunol Inflamm
November 2024
Ophthalmology Department, "Fondazione Policlinico Universitario A. Gemelli, IRCCS", Rome, Italy.
Systemic sclerosis (SSc) is a chronic multisystemic disease characterized by immunological activation, diffuse vasculopathy, and generalized fibrosis exhibiting a variety of symptoms. A recognized precursor of SSc is Raynaud's phenomenon, which is part of the very early disease of systemic sclerosis (VEDOSS) in combination with nailfold videocapillaroscopy (NVC) impairment. The pathophysiology of ocular involvement, alterations in internal organs, and body integumentary system involvement in SSc patients are complicated and poorly understood, with multiple mechanisms presumptively working together.
View Article and Find Full Text PDFCutaneous Features, Autoantibody Profile, and Nailfold Capillaroscopy of Systemic Sclerosis: A Study of 60 Cases.
J Assoc Physicians India
November 2022
Scientist, National Institute of Immunohaematology, Seth Gordhandas Sunderdas Medical College (GSMC) and King Edward Memorial (KEM) Hospital, Mumbai, Maharashtra, India.
Background: Systemic sclerosis (SSc) is an autoimmune chronic multisystem disorder with a plethora of cutaneous manifestations. These manifestations often may be the only presenting complaint. Early identification of these help in diagnosing grievous systemic manifestations and their prompt and appropriate treatment.
View Article and Find Full Text PDFCorrelations between capillary density and degree of skin pigmentation in healthy children analysed by nailfold video capillaroscopy.
Quant Imaging Med Surg
June 2023
Department of Paediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Centres (AUMC), University of Amsterdam, Amsterdam, The Netherlands.
Background: Nailfold video capillaroscopy (NVC) is a simple, non-invasive diagnostic tool but studies with normal values for capillary density in healthy children are rare. Ethnic background seems to play a role in capillary density; however, this is not well substantiated yet. In this work, we set out to evaluate influence of ethnic background/skin pigmentation and age on capillary density reading in healthy children.
View Article and Find Full Text PDFEffect of skin phototype on quantitative nailfold capillaroscopy.
J Scleroderma Relat Disord
October 2022
All India Institute of Medical Sciences, Bilaspur, India.
Objectives: To determine the impact of Fitzpatrick scale-based skin phototype on visualization of capillary density using nailfold capillaroscopy in healthy Indian adults.
Methods: In this cross-sectional study, healthy adults were examined for nailfold capillaroscopy findings utilizing a portable capillary microscope at 800× magnification. Photographs of two contiguous areas measuring 1 mm each of the distal row of capillaries were captured.
Capillaroscopy in Pigmented Basal Cell Carcinoma Smaller than 3-mm Diameter: A Report of Four Lesions.
Acta Derm Venereol
August 2022
Department of Dermatology, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi, Gunma 371-8511, Japan.
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