AI Article Synopsis
- The study looks at how thymine-thymine (TT) dimers in DNA form, especially when exposed to UV light, by focusing on a specific charge transfer state.
- Measurements indicate that the neighboring nucleobases around the TT site have a low oxidation potential and a long-lasting charge transfer state.
- These characteristics potentially help to lower the buildup of harmful DNA lesions that can be caused by UV radiation.
Article Abstract
DNA-sequence-dependent thymine-thymine (TT) dimerization was investigated from the perspective of the UV-induced charge transfer state. Steady-state and transient absorption measurements suggest that the relatively small oxidation potential and long-lived charge transfer state at the neighboring nucleobases of the TT site may reduce DNA lesion accumulation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d2cc03902h | DOI Listing |
Publication Analysis
Top Keywords
charge transfer
8
transfer state
8
sequence-dependent thymine
4
thymine dimerization
4
dimerization lifetimes
4
lifetimes photoexcited
4
photoexcited state
4
state oligonucleotides
4
oligonucleotides dna-sequence-dependent
4
dna-sequence-dependent thymine-thymine
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!