Lobar atelectasis may be a complication of pulmonary exacerbations in cystic fibrosis (CF). There are no established guidelines on the management of this condition in patients with CF. Therapeutic bronchoscopy with recombinant human deoxyribonuclease (rhDNase) instillation has been described to be successful in patients not responding to conservative measures. We describe a case of a young man with CF, with previously mild impaired lung function, presenting with cough, desaturation, and worsening dyspnea, persisting for over 6 weeks, despite conservative therapy. Thoracic imaging showed right lower lobe atelectasis, which was successfully treated with bronchoscopy and instillation of rhDNase. Long-term resolution of the atelectasis was confirmed with chest magnetic resonance imaging follow-up.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826114 | PMC |
| http://dx.doi.org/10.1002/ppul.26094 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Lymphatic plastic bronchitis: a study based on CT and MR lymphangiography.
BMC Med Imaging
December 2024
Department of Radiology, Beijing Shijitan Hospital, Capital Medical University, Yangfangdian Tieyiyuan Road No.10, Haidian District, Beijing, 100038, China.
Objectives: To investigate the diagnostic value of CT lymphangiography (CTL) and non-contrast MR lymphangiography (MRL) in lymphatic plastic bronchitis.
Materials And Methods: The clinical and imaging data of 31 patients with lymphatic plastic bronchitis diagnosed by clinical, imaging and pathological results were retrospectively analyzed. All patients underwent CTL and MRL.
The effect of bronchoscopic lung volume reduction on the bronchodilator response.
J Thorac Dis
October 2024
Department of Pulmonary and Critical Care Medicine, St. Luke's University Health Network, Bethlehem, PA, USA.
Background: Bronchoscopic lung volume reduction (BLVR) is a method of achieving lung collapse in severely emphysematous regions. One of the measures of success is the improvement in post-bronchodilator forced expiratory volume in the first second (FEV). The change in bronchodilator response (BDR) following BLVR is typically not reported, however, the changes in lung physiology that accompany endobronchial valve placement may impact aerosol drug delivery and alter the response to bronchodilators.
View Article and Find Full Text PDFLessons Learned: Risk Factors and Clinical Impact of Severe Pneumothorax After Endoscopic Lung Volume Reduction With Endobronchial Valves.
Chest
November 2024
Department for Pneumology and Critical Care Medicine, Thoraxklinik at University of Heidelberg, Heidelberg, Germany; Translational Lung Research Center Heidelberg, German Center for Lung Research (DZL), Heidelberg, Germany.
Background: Pneumothorax is a major complication after endoscopic lung volume reduction with valves, with a prevalence of up to 34%. Although some patients benefit from valve implantation despite pneumothorax, others are significantly impaired after lung collapse.
Research Question: What are the differences in the severity grades of pneumothorax and how do these affect clinical practice?
Study Design And Methods: This single-center retrospective study analyzed patients undergoing endoscopic valve implantation with and without pneumothorax after intervention.
Appropriateness of respiratory physiotherapy positioning for acute lobar collapse.
Aust Crit Care
September 2024
Physiotherapy Department, St Vincent's Hospital, Sydney, Australia. Electronic address:
Background: Positioning is an important physiotherapy treatment modality for the management of aeration loss associated with acute lobar atelectasis (ALA). Physiotherapists typically rely on lung auscultation and interpretation of chest x-ray (CXR) to inform treatment selection. These tools lack diagnostic accuracy, which could limit the ability of a physiotherapist to locate ALA and select an appropriate treatment position.
View Article and Find Full Text PDFTracheobronchomalacia is common in children with primary ciliary dyskinesia-A case note review.
Pediatr Pulmonol
December 2024
Paediatric Department of Allergy and Lung Diseases, Oslo University Hospital, Oslo, Norway.
Background: The estimated prevalence of tracheobronchomalacia (TBM) in children is about 1:2100. Prevalence of intrathoracic malacia is higher in children with chronic lung disease such as bronchiectasis and cystic fibrosis (CF) and may contribute to increased morbidity.
Objective: To determine the prevalence and assess clinical features of tracheomalacia (TM), TBM and bronchomalacia (BM) in patients with primary ciliary dyskinesia (PCD).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!